ReviewJournal of the American Academy of Dermatology2019
Approaches to limit systemic antibiotic use in acne: Systemic alternatives, emerging topical therapies, dietary modification, and laser and light-based treatments.
Review in Journal of the American Academy of Dermatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06909344 (Effectiveness and Safety of 577-nm Diode Laser in the Treatment of Non -Inflammatory Acne), which is not on this map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness and Safety of 577-nm Diode Laser in the Treatment of Non -Inflammatory Acne
Who cites it
41 citing papers in PubMed, 106 citations in OpenAlex.
- Efficacy of Spironolactone Compared with Doxycycline in Moderate Acne in Adult Females: Results of the Multicentre, Controlled, Randomized, Double-blind Prospective and Parallel Female Acne Spironolactone vs doxyCycline Efficacy (FASCE) Study.Acta dermato-venereologica · 2024Trial
- Trial
- Trial
- Therapeutic Journey Among Patients with Acne Treated with Isotretinoin.Dermatology and therapy · 2026Article
- Green-synthesized metal oxide nanoparticles enhance the antibacterial activity of Portulaca oleracea through foliar nano-elicitation.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Oral and Topical Spironolactone in Adult Female Acne: A Narrative Review Comparing Systemic and Local Approaches.Clinical, cosmetic and investigational dermatology · 2026Review
- Pharmacovigilance profiles of three generations of mineralocorticoid receptor antagonists and network toxicology analysis.Frontiers in medicine · 2026Article
- The most influential research in laser therapy for acne and acne scars: A bibliometric analysis.Lasers in medical science · 2025Review
- Established and Emerging Laser Treatments for Acne Vulgaris in Diverse Skin Types.The Journal of clinical and aesthetic dermatology · 2025Review
- Challenges in designing a randomized, double-blind noninferiority trial for treatment of acne: The SD-ACNE trial.Clinical trials (London, England) · 2025Article
- Article
- Risk and timing of isotretinoin-related laboratory disturbances: a population-based study.International journal of dermatology · 2024Article
- Efficacy and Safety of Solid-state Dual-wavelength Lasers for the Treatment of Moderate-to-severe Inflammatory Acne in Asian Populations.Plastic and reconstructive surgery. Global open · 2024Article
- Effectiveness of spironolactone for women with acne vulgaris (SAFA) trial: a critically appraised topic.The British journal of dermatology · 2023Article
- The Personalized Acne Treatment Tool - Recommendations to facilitate a patient-centered approach to acne management from the Personalizing Acne: Consensus of Experts.JAAD international · 2023Article
- Review
- Systematic review of clinical practice guidelines for acne vulgaris published between January 2017 and July 2021.Skin health and disease · 2023Article
- The updates and implications of cutaneous microbiota in acne.Cell & bioscience · 2023Review
- A propensity score matched cohort study identifying an association of acne, but not oral antibiotic or isotretinoin use, with risk of incident inflammatory bowel disease.Journal of the American Academy of Dermatology · 2023Article
- Therapeutic Efficacy of Bovine Basic Fibroblast Growth Factor Combined with Ultrapulsed Fractional COClinical, cosmetic and investigational dermatology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Acne is one of the most common diseases worldwide and affects ∼50 million individuals in the United States. Oral antibiotics are the most common systemic agent prescribed for the treatment of acne. However, their use might be associated with a variety of adverse outcomes including bacterial resistance and disruption of the microbiome. As a result, multiple treatment guidelines call for limiting the use of oral antibiotics in the treatment of acne, although actual prescribing often does not follow these guidelines. In this review, the rationale for concerns regarding the use of oral antibiotics for the management of acne is reviewed. In addition, we will discuss our approach to complying with the intent of the guidelines, with a focus on novel topical agents, dietary modification, laser and light-based modalities, and systemic medications, such as spironolactone, combined oral contraceptives, and oral isotretinoin.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.