Evidence map›Paper›PMID 30296097›Full record

ArticleJournal of proteome research2019

Precision Medicine: Role of Proteomics in Changing Clinical Management and Care.

Jennifer E Van Eyk, Michael P Snyder

Abstract read
In one paragraph

Article in Journal of proteome research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. The Role of Clinical Glyco(proteo)mics in Precision Medicine.Molecular & cellular proteomics : MCP · 2023
    Article
  10. Multi-Omics Profiling for Health.Molecular & cellular proteomics : MCP · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Novel Strategies to Address the Challenges in Top-Down Proteomics.Journal of the American Society for Mass Spectrometry · 2021
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jennifer E Van EykAdvanced Clinical Biosystems Research Institute, The Smidt Heart Institute , Cedars Sinai Medical Center , Los Angeles , California 90048 , United States.ORCID 0000-0001-9050-148X
Michael P SnyderDepartment of Genetics , Stanford University School of Medicine , Stanford , California 94305 , United States.

Funding

Pathobiology of Cardiac Dyssynchrony &ResynchronizationP01HL077180 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI KASS, DAVID ALAN · 2004 to 2014
$22.8M
Genomic and Proteomic Architecture of AtherosclerosisR01HL111362 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HERRINGTON, DAVID MCLEOD · 2012 to 2021
$17.2M
Integrative Omics as a Discovery Tool for Pulmonary HypertensionR01HL122887 · NHLBI · STANFORD UNIVERSITY · PI NICOLLS, MARK ROBERT, RABINOVITCH, MARLENE · 2015 to 2018
$4.1M
Exosome Therapeutics to Dissect HFpEF MechanismsR01HL155346 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI MARBAN, EDUARDO, VAN EYK, JENNIFER E · 2021 to 2024
$3.3M
Design and Validation of Easy-to-Adopt Mass Spectrometry Assays of Importance to ObesityU01DK124019 · NIDDK · CEDARS-SINAI MEDICAL CENTER · PI SOBHANI, KIMIA, VAN EYK, JENNIFER E · 2019 to 2022
$3.1M
Mitochondrial Turnover in the Human HeartR01HL132075 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI GOTTLIEB, ROBERTA A., VAN EYK, JENNIFER E · 2017 to 2020
$2.1M
Post-translational modification and protein quantification of plasma and CSFU01NS115658 · NINDS · CEDARS-SINAI MEDICAL CENTER · PI SOBHANI, KIMIA, VAN EYK, JENNIFER E · 2019 to 2019
$1.9M
NHLBI PROTEOMICS INITIATIVE-N01HV28180-268028180-268028180N01HV028180 · HV · JOHNS HOPKINS UNIVERSITY · PI VAN EYK, JENNIFER E · 2002 to 2006
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NHLBI NIH HHS N01 HV028180NHLBI NIH HHS P01 HL077180NHLBI NIH HHS R01 HL111362NHLBI NIH HHS R01 HL122887NHLBI NIH HHS R01 HL132075NHLBI NIH HHS R01 HL155346NIDDK NIH HHS U01 DK124019NINDS NIH HHS U01 NS115658
6 · The paper itself

Abstract

It is now possible to collect large sums of health-related data which has the potential to transform healthcare. Proteomics, with its central position as downstream of genetics and epigenetic inputs and upstream of biochemical outputs and integrators of environmental signals, is well-positioned to contribute to health discoveries and management. We present our perspective on the role of proteomics and other Omics in precision health and medicine.

Indexed as

AgingBiomarkersData CollectionDelivery of Health CareEpigenomicsForecastingHumansMachine LearningPhenotypePrecision MedicineProteomeProteomicsRisk AssessmentBiomarkersProteomebig dataindividualized medicinemass spectrometryprecision medicineproteomicsremote monitoring

Identifiers

PMID30296097
PMCPMC10372929

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.