ArticleNeuro-oncology2019
Nonmalignant and malignant meningioma incidence and survival in the elderly, 2005-2015, using the Central Brain Tumor Registry of the United States.
Article in Neuro-oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.
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Who cites it
53 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.
- Epidemiology of Cancer in Older Adults: A Systematic Review.Current oncology reports · 2024Pooled it
- Meningiomas in Elderly Patients: Epidemiology, Clinical Characteristics, Prognostic Factors, and Personalized Treatment Strategies.Revista de neurologia · 2026Review
- Beyond Chronological Age: A Scoping Review of Neurosurgical Intervention for Central Nervous System Tumors in the Very Elderly.Current oncology (Toronto, Ont.) · 2026Article
- SWI combined with cMRI and CT in the differentiating of intracranial Rosai-Dorfman disease from fibrous meningioma.BMC medical imaging · 2026Article
- Post-traumatic meningioma or coincidental occurrence? A case report and critical review of the literature.Surgical neurology international · 2026Article
- Combined interventional and craniotomy surgery for meningioma apoplexy complicated by acute subdural hematoma: a case report and literature review.Frontiers in surgery · 2026Article
- Single-stage microscopic and endoscopic resection of spatially separate meningiomas through a single craniotomy.Surgical neurology international · 2026Article
- Development and validation of a prognostic nomogram for overall survival in individuals with malignant meningiomas: a population-based study.Scientific reports · 2025Article
- Racial or Ethnic Disparities in Incidence, Treatment, and Prognosis of Adult Intracranial Meningiomas.Journal of racial and ethnic health disparities · 2025Article
- Integrative bioinformatics analysis and elastic network modeling elucidate the role of cellular senescence in meningioma recurrence.Discover oncology · 2025Article
- Single-cell transcriptomic analysis reveals metastatic and immunosuppressive characteristics in meningioma brain-tumor interface.Journal of translational medicine · 2025Article
- The prognostic role of frailty on outcomes following meningioma resection in the elderly: a matched analysis employing baseline functional status.Acta neurochirurgica · 2025Article
- Incidence, Mortality and Survival Time Trends of Brain and CNS Tumours in the Canton of Zurich (Switzerland) Between 1980 and 2021.Cancer medicine · 2025Article
- Segmenting the Global Layers of Malignant Meningioma: A Population-Based Study of Incidence, Risk Factors, and Temporal Trends.Brain and behavior · 2025Article
- A retrospective comparison of active surveillance to stereotactic radiosurgery for the management of elderly patients with an incidental meningioma.Acta neurochirurgica · 2025Article
- Pre- and Post-operative Parameters among Patients Undergoing Pre-operative Embolization of Meningioma: a Tertiary Referral Center Experience.Acta medica Philippina · 2025Article
- Hyperostotic meningiomas in children. A case-based update.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Review
- Optimizing the use of Ki-67 proliferative index as a prognostic biomarker in meningiomas using digital analysis.Journal of neurosurgery · 2024Article
- Benign extracranial meningioma with pulmonary metastasis: a case report and review of literature.Journal of medical case reports · 2024Review
- Malignant Neoplasm of the Meninges: A 20-Year Retrospective Study to Assess Trends and Disparities in Place of Death.Cureus · 2024Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMeningioma incidence increases significantly with age. In the expanding elderly population, we lack complete understanding of population-based trends in meningioma incidence/survival. We provide an updated, comprehensive analysis of meningioma incidence and survival for individuals aged over 65.
methodsData were obtained from the Central Brain Tumor Registry of the United States (CBTRUS) from 2005-2015 for nonmalignant and malignant meningioma. Age-adjusted incidence rates per 100000 person-years were analyzed by age, sex, race, ethnicity, location, and treatment modalities. Survival was analyzed using Kaplan-Meier and multivariable Cox proportional hazards models for a subset of CBTRUS data.
resultsNonmalignant meningioma incidence doubled from adults age 65-69 years to adults over age 85 years and was significantly greater in females than males for all ages. Malignant meningioma incidence did not differ by sex for any age grouping. Nonmalignant and malignant meningioma incidence was significantly greater in black populations versus others. Nonmalignant meningioma survival was worse with age, in black populations, and in males, including when analyzed by 5-year age groups. Surgical resection and radiation did not improve survival compared with resection alone in nonmalignant meningioma.
conclusionsThis study reports increasing nonmalignant meningioma incidence in the elderly, increased incidence in black populations, and in females. In contrast, malignant meningioma incidence did not differ between sexes. Risk of death was higher for black individuals and males. Additionally, radiation did not confer a survival advantage when combined with resection for nonmalignant meningioma. Thus, we identify clinically relevant discrepancies in meningioma incidence/survival that require further study.
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