Evidence map›Paper›PMID 30295724›Full record

ArticleDatabase : the journal of biological databases and curation2018

Extracting chemical-protein relations using attention-based neural networks.

Sijia Liu, Feichen Shen, Ravikumar Komandur Elayavilli, Yanshan Wang, Majid Rastegar-Mojarad, Vipin Chaudhary, Hongfang Liu

Abstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Prompt Tuning in Biomedical Relation Extraction.Journal of healthcare informatics research · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Extraction of causal relations based on SBEL and BERT model.Database : the journal of biological databases and curation · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sijia LiuDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Feichen ShenDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Ravikumar Komandur ElayavilliDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Yanshan WangDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Majid Rastegar-MojaradDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Vipin ChaudharyDepartment of Computer Science and Engineering, University at Buffalo, Buffalo, NY, USA.
Hongfang LiuDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.

Funding

Open Health Natural Language Processing CollaboratoryU01TR002062 · NCATS · MAYO CLINIC ROCHESTER · PI JIANG, XIAOQIAN, LIU, HONGFANG · 2017 to 2021
$7.6M
Semi-structured Information Retrieval in Clinical Text for Cohort IdentificationR01LM011934 · NLM · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI HERSH, WILLIAM R, LIU, HONGFANG · 2014 to 2025
$5.1M
Secondary use of EMRs for surgical complication surveillanceR01EB019403 · NIBIB · MAYO CLINIC ROCHESTER · PI LIU, HONGFANG, STORLIE, CURTIS · 2015 to 2022
$3.8M
Enabling Comparative Effectiveness Research in Silent Brain Infarction Through Natural Language Processing and Big DataR01NS102233 · NINDS · TUFTS MEDICAL CENTER · PI DAVID M KENT · 2017 to 2026
$3.4M
Patient Medical History Representation, Extraction, and Inference from EHR DataR01LM011829 · NLM · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI TAO, CUI · 2014 to 2018
$1.7M
NLM NIH HHS R01 LM011829
6 · The paper itself

Abstract

Relation extraction is an important task in the field of natural language processing. In this paper, we describe our approach for the BioCreative VI Task 5: text mining chemical-protein interactions. We investigate multiple deep neural network (DNN) models, including convolutional neural networks, recurrent neural networks (RNNs) and attention-based (ATT-) RNNs (ATT-RNNs) to extract chemical-protein relations. Our experimental results indicate that ATT-RNN models outperform the same models without using attention and the ATT-gated recurrent unit (ATT-GRU) achieves the best performing micro average F1 score of 0.527 on the test set among the tested DNNs. In addition, the result of word-level attention weights also shows that attention mechanism is effective on selecting the most important trigger words when trained with semantic relation labels without the need of semantic parsing and feature engineering. The source code of this work is available at https://github.com/ohnlp/att-chemprot.

Indexed as

AlgorithmsDatabases, ChemicalDatabases, ProteinNeural Networks, ComputerProteinsProteins

Identifiers

PMID30295724
PMCPMC6174551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.