Trial reportDiseases of the esophagus : official journal of the International Society for Diseases of the Esophagus2019
Effect of preoperative inspiratory muscle training on physical functioning following esophagectomy.
Trial report in Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 8 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 8 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Pooled it
- Effects of different rehabilitation strategies on physical function and complications in postoperative patients with esophageal cancer: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Efficacy of Prehabilitation in cancer patients: an Rcts systematic review with meta-analysis.BMC cancer · 2024Pooled it
- Pooled it
- Effects of unimodal or multimodal prehabilitation on patients undergoing surgery for esophagogastric cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Pooled it
- Surgical Apgar score could predict complications after esophagectomy: a systematic review and meta-analysis.Interactive cardiovascular and thoracic surgery · 2022Pooled it
- Physiotherapy Regimens in Esophagectomy and Gastrectomy: a Systematic Review and Meta-Analysis.Annals of surgical oncology · 2022Pooled it
- Impact of prehabilitation on objectively measured physical activity levels in elective surgery patients: a systematic review.BMJ open · 2021Pooled it
- Respiratory muscle training with electronic devices in the postoperative period of hepatectomy: A randomized study.World journal of hepatology · 2023Trial
- Association of Preoperative Inspiratory Muscle Weakness and Respiratory Sarcopenia with Postoperative Pneumonia Following Esophagectomy: A Multicenter Retrospective Cohort Study.Annals of surgical oncology · 2026Article
- Effect of prehabilitation in patients undergoing gastric or oesophageal cancer resections: A systematic review and meta-analysis.World journal of gastrointestinal endoscopy · 2025Article
- Feasibility, safety and preliminary effect of exercise prehabilitation in patients with esophageal cancer undergoing surgery: an open-label, randomized, parallel-group pilot and feasibility study.BMC sports science, medicine & rehabilitation · 2025Article
- Measurement and optimization of perioperative risk among patients undergoing surgery for esophageal cancer.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2024Article
- Whole-process nursing management for laparo-gastroscopic esophagectomy.Journal of gastrointestinal oncology · 2022Article
- Predictive model of postoperative pneumonia after neoadjuvant immunochemotherapy for esophageal cancer.Journal of gastrointestinal oncology · 2022Article
- Article
- Effects of Prehabilitation on Functional Capacity in Aged Patients Undergoing Cardiothoracic Surgeries: A Systematic Review.Healthcare (Basel, Switzerland) · 2021Review
- Effectiveness of telerehabilitation on short-term quality of life of patients after esophageal cancer surgery during COVID-19: a single-center, randomized, controlled study.Journal of gastrointestinal oncology · 2021Article
- Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
Abstract
This study aims to examine the effect of preoperative inspiratory muscle training (IMT) on pre- and postoperative functional exercise performance in patients undergoing esophagectomy. A subcohort of patients recruited to the PREPARE randomized control trial were studied. Following evaluation of respiratory muscle function (spirometry, maximum inspiratory pressure (MIP), and inspiratory muscle endurance), postoperative mobilization (accelerometry) and postoperative physical functioning (6-minute walk test (6MWT)), participants scheduled for esophagectomy were randomly assigned to either 2 weeks of preoperative IMT or a control group. Measures were repeated on the day before surgery and postoperatively. Sixty participants (mean (standard deviation) age 64.13 (7.8) years; n = 42 male; n = 43 transthoracic esophagectomy; n = 17 transhiatial esophagectomy) were included in the final analysis (n = 28 IMT; n = 32 control). There was a significant improvement in preoperative MIP (P = 0.03) and inspiratory muscle endurance (P = 0.04); however preoperative 6MWT distance did not change. Postoperatively, control participants were more active on postoperative day (POD)1, and from POD1-POD5 (P = 0.04). Predischarge, 6MWT distance was significantly lower in the IMT group (305.61 (116.3) m) compared to controls (380.2 (47.1) m, P = 0.03). Despite an increase in preoperative respiratory muscle function, preoperative IMT does not improve pre- or postoperative physical functioning or postoperative mobilization following esophagectomy.
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