Evidence map›Paper›PMID 30295664›Full record

ArticleJournal of visualized experiments : JoVE2018

Transcranial Direct Current Stimulation (tDCS) in Mice.

Eduardo de Souza Nicolau, Kevin Augusto Farias de Alvarenga, Helia Tenza-Ferrer, Matheus Carvalho Alves Nogueira, Fernanda Donizete Rezende, Nycolle Ferreira Nicolau, Mélcar Collodetti, Débora Marques de Miranda, Luiz Alexandre Viana Magno, Marco Aurélio Romano-Silva

Abstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eduardo de Souza NicolauCentro de Tecnologia em Medicina Molecular (CTMM), Faculdade de Medicina, Universidade Federal de Minas Gerais.
Kevin Augusto Farias de AlvarengaCentro de Tecnologia em Medicina Molecular (CTMM), Faculdade de Medicina, Universidade Federal de Minas Gerais.
Helia Tenza-FerrerCentro de Tecnologia em Medicina Molecular (CTMM), Faculdade de Medicina, Universidade Federal de Minas Gerais.
Matheus Carvalho Alves NogueiraCentro de Tecnologia em Medicina Molecular (CTMM), Faculdade de Medicina, Universidade Federal de Minas Gerais.
Fernanda Donizete RezendeCentro de Tecnologia em Medicina Molecular (CTMM), Faculdade de Medicina, Universidade Federal de Minas Gerais.
Nycolle Ferreira NicolauCentro de Tecnologia em Medicina Molecular (CTMM), Faculdade de Medicina, Universidade Federal de Minas Gerais.
Mélcar CollodettiCentro de Tecnologia em Medicina Molecular (CTMM), Faculdade de Medicina, Universidade Federal de Minas Gerais.
Débora Marques de MirandaCentro de Tecnologia em Medicina Molecular (CTMM), Faculdade de Medicina, Universidade Federal de Minas Gerais.
Luiz Alexandre Viana MagnoCentro de Tecnologia em Medicina Molecular (CTMM), Faculdade de Medicina, Universidade Federal de Minas Gerais.
Marco Aurélio Romano-SilvaCentro de Tecnologia em Medicina Molecular (CTMM), Faculdade de Medicina, Universidade Federal de Minas Gerais; romano-silva@ufmg.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique proposed as an alternative or complementary treatment for several neuropsychiatric diseases. The biological effects of tDCS are not fully understood, which is in part explained due to the difficulty in obtaining human brain tissue. This protocol describes a tDCS mouse model that uses a chronically implanted electrode allowing the study of the long-lasting biological effects of tDCS. In this experimental model, tDCS changes the cortical gene expression and offers a prominent contribution to the understanding of the rationale for its therapeutic use.

Indexed as

Electrodes, ImplantedAnimalsBrainHumansMiceTranscranial Direct Current Stimulation

Identifiers

PMID30295664
PMCPMC6235291

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.