Trial reportJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2019
Dysfunctional cerebral autoregulation is associated with delirium in critically ill adults.
Trial report in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- The Use of Near-Infrared Spectroscopy and/or Transcranial Doppler as Non-Invasive Markers of Cerebral Perfusion in Adult Sepsis Patients With Delirium: A Systematic Review.Journal of intensive care medicine · 2022Pooled it
- Trial
- Transcranial Doppler ultrasonography in geriatric anesthesia: moving toward personalized brain protection strategies.Anesthesia and pain medicine · 2026Review
- Feasibility of Calculating and Maintaining Near-Infrared Spectroscopy-Guided Personalized Mean Arterial Pressure Targets in Adults With Critical Illness: A Pilot Clinical Study.Critical care explorations · 2026Article
- The Effect of Impaired Cerebral Autoregulation on Postoperative Delirium in Neonates and Infants After Corrective Cardiac Surgery: A Study on Modifiable Risk Factors for Delirium.Reviews in cardiovascular medicine · 2025Article
- Individualized mean arterial pressure targets in critically ill patients guided by non-invasive cerebral-autoregulation: a scoping review.Critical care (London, England) · 2025Article
- Post-anesthesia care unit delirium in children with moyamoya disease undergoing indirect revascularization: incidence and risk factors.Korean journal of anesthesiology · 2025Article
- Association between perioperative rate pressure product and postoperative delirium in geriatric patients with hip fracture.Frontiers in medicine · 2025Article
- Restoring brain connectivity by phrenic nerve stimulation in sedated and mechanically ventilated patients.Communications medicine · 2024Article
- Cerebral autoregulation-directed optimal blood pressure management reduced the risk of delirium in patients with septic shock.Journal of intensive medicine · 2024Article
- Microvascular Autoregulation in Skeletal Muscle Using Near-Infrared Spectroscopy and Derivation of Optimal Mean Arterial Pressure in the ICU: Pilot Study and Comparison With Cerebral Near-Infrared Spectroscopy.Critical care explorations · 2024Observational
- Future of neurocritical care: Integrating neurophysics, multimodal monitoring, and machine learning.World journal of critical care medicine · 2024Review
- Diffuse optical tomography for mapping cerebral hemodynamics and functional connectivity in delirium.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Cerebral autoregulation-based mean arterial pressure targets and delirium in critically ill adults without brain injury: a retrospective cohort study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024Article
- Review
- Article
- Automated machine learning-based model for the prediction of delirium in patients after surgery for degenerative spinal disease.CNS neuroscience & therapeutics · 2023Article
- Comparison of logistic regression and machine learning methods for predicting postoperative delirium in elderly patients: A retrospective study.CNS neuroscience & therapeutics · 2023Article
- Multimodal and autoregulation monitoring in the neurointensive care unit.Frontiers in neurology · 2023Review
- Diaphragm Neurostimulation Mitigates Ventilation-Associated Brain Injury in a Preclinical Acute Respiratory Distress Syndrome Model.Critical care explorations · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Delirium is common during critical illness and is associated with morbidity and mortality, but its pathophysiology is unknown. We tested whether dysfunctional cerebral autoregulation (CA) contributes to the development of delirium. Adult patients (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.