ArticleThe journal of physical chemistry. A2018
Chemical Exchange Reaction Effect on Polarization Transfer Efficiency in SLIC-SABRE.
Article in The journal of physical chemistry. A, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed.
- Nonresonant SABRE provides an additional versatile hyperpolarization approach in magnetic resonance.Science advances · 2026Article
- High-resolution microtesla in-situJournal of magnetic resonance (San Diego, Calif. : 1997) · 2026Article
- Mechanistic insights into chemical exchange during the signal amplification by reversible exchange sensitization of pyruvate.Nature communications · 2026Article
- From Unlocking Pyruvate Hyperpolarization by Signal Amplification by Reversible Exchange (SABRE) to Clinical Prospects.ACS omega · 2026Review
- Multidimensional pH-Temperature Mapping of SABRE-SHEATHThe journal of physical chemistry. B · 2025Article
- Scalable Hyperpolarized MRI Enabled by Ace-SABRE of [1-Angewandte Chemie (International ed. in English) · 2025Article
- Analysis of chemical exchange in iridium N-heterocyclic carbene complexes using heteronuclear parahydrogen-enhanced NMR.Communications chemistry · 2024Article
- Modeling Ligand Exchange Kinetics in Iridium Complexes Catalyzing SABRE Nuclear Spin Hyperpolarization.Analytical chemistry · 2024Article
- Article
- Reversible Parahydrogen Induced Hyperpolarization ofAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- LIGHT-SABRE Hyperpolarizes 1-The journal of physical chemistry. C, Nanomaterials and interfaces · 2023Article
- Spin Hyperpolarization in Modern Magnetic Resonance.Chemical reviews · 2023Review
- Subsecond Three-Dimensional Nitrogen-15 Magnetic Resonance Imaging Facilitated by Parahydrogen-Based Hyperpolarization.The journal of physical chemistry letters · 2022Article
- RapidAnalytical chemistry · 2022Article
- Recent advances in the application of parahydrogen in catalysis and biochemistry.RSC advances · 2022Review
- Phase coherent excitation of SABRE permits simultaneous hyperpolarization of multiple targets at high magnetic field.Physical chemistry chemical physics : PCCP · 2022Article
- Improving SABRE hyperpolarization with highly nonintuitive pulse sequences: Moving beyond avoided crossings to describe dynamics.Science advances · 2022Article
- Synthetic Approaches forChemistry (Weinheim an der Bergstrasse, Germany) · 2021Review
- Synthesis andChemphyschem : a European journal of chemical physics and physical chemistry · 2021Article
- Parahydrogen-Induced Hyperpolarization of Gases.Angewandte Chemie (International ed. in English) · 2020Review
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Signal Amplification By Reversible Exchange (SABRE) is a new and rapidly developing hyperpolarization technique. The recent discovery of Spin-Lock Induced Crossing SABRE (SLIC-SABRE) showed that high field hyperpolarization transfer techniques developed so far were optimized for singlet spin order that does not coincide with the experimentally produced spin state. Here, we investigated the SLIC-SABRE approach and the most advanced quantitative theoretical SABRE model to date. Our goal is to achieve the highest possible polarization with SLIC-SABRE at high field using the standard SABRE system, IrIMes catalyst with pyridine. We demonstrated the accuracy of the SABRE model describing the effects of various physical parameters such as the amplitude and frequency of the radio frequency field, and the effects of chemical parameters such as the exchange rate constants. By fitting the model to the experimental data, the effective life time of the SABRE complex was estimated, as well as the entropy and enthalpy of the complex-dissociation reaction. We show, for the first time, that this SLIC-SABRE model can be useful for the evaluation of the chemical exchange parameters that are very important for the production of highly polarized contrast agents via SABRE.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.