Evidence map›Paper›PMID 30295319›Full record

Trial reportChild development2019

A Family Focused Intervention Influences Hippocampal-Prefrontal Connectivity Through Gains in Self-Regulation.

Jamie L Hanson, Alysha D Gillmore, Tianyi Yu, Christopher J Holmes, Emily S Hallowell, Allen W Barton, Steven R H Beach, Adrianna Galván, James MacKillop, Michael Windle and 4 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Child development, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Positive affect as a developmental mediator of early adversity and internalizing psychopathology.Journal of child psychology and psychiatry, and allied disciplines · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Addiction as a brain disease revised: why it still matters, and the need for consilience.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Review
  14. Article
  15. Socioeconomic Risk for Adolescent Cognitive Control and Emerging Risk-Taking Behaviors.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2021
    Article
  16. Neurobiological Markers of Resilience to Early-Life Adversity During Adolescence.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2021
    Review
  17. Article
  18. Testosterone and hippocampal trajectories mediate relationship of poverty to emotion dysregulation and depression.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jamie L HansonUniversity of Pittsburgh.ORCID 0000-0002-0469-8886
Alysha D GillmoreUniversity of Pittsburgh.
Tianyi YuUniversity of Georgia.
Christopher J HolmesUniversity of Georgia.
Emily S HallowellUniversity of Georgia.
Allen W BartonUniversity of Georgia.
Steven R H BeachUniversity of Georgia.
Adrianna GalvánUniversity of California, Los Angeles.
James MacKillopMcMaster University.
Michael WindleEmory University.
Edith ChenNorthwestern University.
Gregory E MillerNorthwestern University.
Lawrence H SweetUniversity of Georgia.
Gene H BrodyUniversity of Georgia.

Funding

RURAL AFRICAN AMERICAN YOUNG ADULTS' PATHWAYS TO PSYCHOSOCIAL AND PHYSICAL HEALTHR01HD030588 · NICHD · UNIVERSITY OF GEORGIA (UGA) · PI EHRLICH, KATHERINE BABCOCK · 1993 to 2023
$12.0M
Vulnerability to Drug Use & HIV: Advancing Prevention for Rural African AmericansP30DA027827 · NIDA · UNIVERSITY OF GEORGIA · PI BRODY, GENE H. · 2009 to 2018
$10.2M
The Development of Alcohol Use and Alcohol Disorders Across the LifespanK05AA021143 · NIAAA · EMORY UNIVERSITY · PI WINDLE, MICHAEL T · 2012 to 2016
$1.0M
NIAAA NIH HHS K05 AA021143NICHD NIH HHS R01 HD030588NIDA NIH HHS P30 DA027827
6 · The paper itself

Abstract

The stressors associated with poverty increase the risks for externalizing psychopathology; however, specific patterns of neurobiology and higher self-regulation may buffer against these effects. This study leveraged a randomized control trial, aimed at increasing self-regulation at ~11 years of age. As adults, these same individuals completed functional MRI scanning (M

Indexed as

Child BehaviorConnectomeFamily TherapySelf-ControlAdultBehavioral SymptomsChildFemaleHippocampusHumansMagnetic Resonance ImagingMalePrefrontal CortexYoung Adult

Identifiers

PMID30295319
PMCPMC6453760

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.