Evidence map›Paper›PMID 30295012›Full record

ReviewMacromolecular bioscience2019

Stimuli-Responsive Supramolecular Hydrogels and Their Applications in Regenerative Medicine.

Jiaul Hoque, Nivedita Sangaj, Shyni Varghese

Abstract readReview
In one paragraph

Review in Macromolecular bioscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
  2. Electrochemically Triggered Supramolecular Polymerization Under Kinetic Control.Angewandte Chemie (International ed. in English) · 2026
    Article
  3. Review
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  5. Article
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  8. Synthesis of tetrazole hybridized with thiazole, thiophene or thiadiazole derivatives, molecular modelling and antimicrobial activity.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  9. Review
  10. Article
  11. Article
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jiaul HoqueDepartment of Orthopaedic Surgery, Duke University, Durham, 27710, NC.
Nivedita SangajDepartment of Orthopaedic Surgery, Duke University, Durham, 27710, NC.
Shyni VargheseDepartment of Orthopaedic Surgery, Duke University, Durham, 27710, NC.

Funding

Adenosine A2B Receptor in Bone Health and OsteoporosisR01AR071552 · NIAMS · DUKE UNIVERSITY · PI VARGHESE, SHYNI · 2017 to 2021
$2.4M
Diversity Supplement -"Bioinspired Synthetic Grafts for Bone Regeneration"R01AR063184 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI VARGHESE, SHYNI · 2013 to 2017
$1.7M
NIAMS NIH HHS R01 AR063184NIAMS NIH HHS R01 AR071552
6 · The paper itself

Abstract

Supramolecular hydrogels are a class of self-assembled network structures formed via non-covalent interactions of the hydrogelators. These hydrogels capable of responding to external stimuli are considered to be smart materials due to their ability to undergo sol-gel and/or gel-sol transition upon subtle changes in their surroundings. Such stimuli-responsive hydrogels are intriguing biomaterials with applications in tissue engineering, delivery of cells and drugs, modulating tissue environment to promote innate tissue repair, and imaging for medical diagnostics among others. This review summarizes the recent developments in stimuli-responsive supramolecular hydrogels and their potential applications in regenerative medicine. Specifically, various structural aspects of supramolecular hydrogelators involved in self-assembly, the role of external stimuli in tuning/controlling their phase transitions, and how these functions could be harnessed to advance applications in regenerative medicine are focused on. Finally, the key challenges and future prospects for these versatile materials are briefly described.

Indexed as

Biocompatible MaterialsHydrogelsHumansRegenerative MedicineTissue EngineeringBiocompatible MaterialsHydrogelshydrogelatorsregenerative medicineself-assemblystimulisupramolecular hydrogels

Identifiers

PMID30295012
PMCPMC6333493

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.