Evidence map›Paper›PMID 30294940›Full record

ArticleJournal of veterinary internal medicine2018

Spontaneous primary hypothyroidism in 7 adult cats.

Mark E Peterson, Marcia A Carothers, David A Gamble, Mark Rishniw

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Spontaneous adult-onset primary hypothyroidism in 17 cats.Journal of feline medicine and surgery · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Feline congenital hypothyroidism: a case report.Brazilian journal of veterinary medicine · 2023
    Article
  8. Article
  9. Review
  10. Infertility In Queens: Clinical approach, experiences and challenges.Journal of feline medicine and surgery · 2022
    Review
  11. Article
  12. Article
  13. Spontaneous primary hypothyroidism in 7 adult cats.Journal of veterinary internal medicine · 2018
    Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Mark E PetersonAnimal Endocrine Clinic, New York.ORCID https://orcid.org/0000-0002-3016-1855
Marcia A CarothersAkron Veterinary Internal Medical Practice, Copley, Ohio.
David A GambleAntech Laboratories, Inc., Lake Success, New York.
Mark RishniwCollege of Veterinary Medicine, Cornell University, Ithaca, New York.
Cornell University · USCleveland Clinic Akron General · USMTECH Laboratories (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNaturally occurring hypothyroidism in adult cats is rare, with only 4 cases reported.

objectivesTo describe the historical, clinical, laboratory, and scintigraphic features of adult cats with spontaneous hypothyroidism. ANIMALS: Seven adult cats referred for suspected hypothyroidism.

methodsProspective case series. We collected data on cats' signalment, clinical signs, results of physical examination, routine laboratory and thyroid hormone testing, and thyroid imaging (thyroid scintigraphy or ultrasound). We subsequently treated cats with levothyroxine and evaluated their response to treatment.

resultsCats ranged from 3.5 to 11 years, with no apparent breed predilection; 6/7 cats were male. Only 2/7 cats were initially tested because of signs of hypothyroidism (hair-coat changes, lethargy, obesity); others were tested for routine thyroid monitoring or palpable thyroid nodules. Four were azotemic (serum creatinine, 2.2-3.4 mg/dL). Six of the cats had low serum thyroxine (T CONCLUSIONS AND CLINICAL IMPORTANCE: Primary hypothyroidism develops in adult cats, with a higher prevalence than previously thought. Most cats appear to develop a goitrous form of hypothyroidism associated with thyroid hyperplasia, whereas thyroid atrophy appears to be less common. With levothyroxine replacement, clinical and laboratory abnormalities improve or resolve.

Indexed as

AnimalsCat DiseasesCatsFemaleHypothyroidismMaleProspective StudiesRadionuclide ImagingThyroid GlandThyrotropinThyroxineUltrasonographyThyrotropinThyroxineatrophicfelinegoitergoitrousthyroid glandthyroxineTSH

Identifiers

PMID30294940
PMCPMC6271337
OpenAlexW2896791143

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.