ReviewJournal of veterinary internal medicine2018
Equine asthma: Integrative biologic relevance of a recently proposed nomenclature.
Review in Journal of veterinary internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed.
- Association of submaximal exercise test variables with diagnosis of asthma in a mixed-breed cohort of leisure horses.Journal of veterinary internal medicine · 2026Article
- Endoscopically assessed mucus parameters in equine asthma: Relationship to clinical history and cytological findings data.Equine veterinary journal · 2026Article
- Multi-Kingdom Fecal Microbiota Alterations in Horses with Severe Equine Asthma.Microorganisms · 2026Article
- Targeting Toll-like Receptor 2: synthetic diacylated lipopeptides polarize equine macrophages towards a pro-inflammatory phenotype.Frontiers in immunology · 2026Article
- The transition from winter to spring has an impact on the airway metabolome profile of asthmatic horses.PloS one · 2026Article
- Equine Asthma Is Characterised by Severity-Dependent Correlations Between Blood Neutrophil Cholesterol Content and NET Formation.European journal of immunology · 2025Article
- MARCKS protein is a potential target in a naturally occurring equine model of neutrophilic asthma.Respiratory research · 2025Article
- Exploring a pico-well based scRNA-seq method (HIVE) for simplified processing of equine bronchoalveolar lavage cells.PloS one · 2025Article
- Clinical variability of equine asthma phenotypes and analysis of diagnostic steps in phenotype differentiation.Acta veterinaria Scandinavica · 2024Article
- The Most Common Environmental Risk Factors for Equine Asthma-A Narrative Review.Animals : an open access journal from MDPI · 2024Review
- The amount of hyaluronic acid and airway remodelling increase with the severity of inflammation in neutrophilic equine asthma.BMC veterinary research · 2024Article
- Equine Asthma Does Not Affect Circulating Myostatin Concentrations in Horses.Animals : an open access journal from MDPI · 2024Article
- Exposure to chemical pollutants and biological aerosol in indoor facilities for recreational and sport horses.BMC veterinary research · 2024Article
- The Microbiota and Equine Asthma: An Integrative View of the Gut-Lung Axis.Animals : an open access journal from MDPI · 2024Review
- Article
- Decision Making in Severe Equine Asthma-Diagnosis and Monitoring.Animals : an open access journal from MDPI · 2023Review
- Lipid species profiling of bronchoalveolar lavage fluid cells of horses housed on two different bedding materials.Scientific reports · 2023Article
- Single-cell transcriptomics delineates the immune cell landscape in equine lower airways and reveals upregulation of FKBP5 in horses with asthma.Scientific reports · 2023Article
- Bronchoalveolar Lavage Cytology in Severe Equine Asthma: Cytocentrifugated versus Sediment Smear Preparations.Veterinary sciences · 2023Article
- Effect of Lavage Solution Type on Bronchoalveolar Lavage Fluid Cytology in Clinically Healthy Horses.Animals : an open access journal from MDPI · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The term "equine asthma" has been proposed as a unifying descriptor of inflammatory airway disease (IAD), recurrent airway obstruction (RAO), and summer pasture-associated obstructive airway disease. Whilst the term will increase comprehensibility for both the lay and scientific communities, its biologic relevance must be compared and contrasted to asthma in human medicine, recognizing the limited availability of peer-reviewed equine-derived data, which are largely restricted to clinical signs, measures of airway obstruction and inflammation and response to therapy. Such limitations constrain meaningful comparisons with human asthma phenotypes. Suggested minimum inclusion criteria supporting the term asthma, as well as similarities and differences between IAD, RAO, and multiple human asthma phenotypes are discussed. Furthermore, differences between phenotype and severity are described, and typical features for equine asthma subcategories are proposed. Based on shared features, we conclude that mild/moderate (IAD) and severe (RAO) equine asthma are biologically appropriate models for both allergic and non-allergic human asthma, with RAO (severe equine asthma) also being an appropriate model for late-onset asthma. With the development of new biologic treatments in humans and the application of more targeted therapeutic approaches in the horse, it would appear appropriate to further investigate the allergic (Th-2) and non-allergic (non-Th-2) phenotypes of equine asthma. Further research is required to more fully determine the potential clinical utility of phenotype classification.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.