ArticleIndian journal of endocrinology and metabolism
A Study of Thyroid Dysfunction in Cirrhosis of Liver and Correlation with Severity of Liver Disease.
Article in Indian journal of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06179368 (Thyoid Dysfucntion; Does it Affect the Short Term Outcome of Heptic Failure Patiens ?), which is not on this map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Thyoid Dysfucntion; Does it Affect the Short Term Outcome of Heptic Failure Patiens ?
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association between thyroid function and nonalcoholic fatty liver disease: a dose-response meta-analysis.Frontiers in endocrinology · 2024Pooled it
- The Clinical Value of Thyroid Hormone Levels and Correlation with Severity of Liver Cirrhosis.Computational intelligence and neuroscience · 2022Pooled it
- Endocrine meets hepatic: the thyroid-liver axis in health and disease-an overview.Wiener medizinische Wochenschrift (1946) · 2026Review
- Thyroid function and outcomes in heart failure with mildly reduced ejection fraction: insights from a large, retrospective registry.Endocrine · 2026Article
- Hypothyroidism and the risk of liver-related events in patients with metabolic dysfunction-associated steatotic liver disease.Clinical and molecular hepatology · 2026Article
- Ameliorative effect of ferulic acid on thyroid dysfunction against propyl-thiouracil induced hypothyroid rats.Endocrine · 2024Article
- Evaluation of MELD Scores and Thyroid Hormones as Prognostic Factors of Liver Cirrhosis.Medicina (Kaunas, Lithuania) · 2024Article
- [Occult thyroid dysfunction in outpatients with liver cirrhosis].Revista medica del Instituto Mexicano del Seguro Social · 2024Article
- Artemisinin ameliorates thyroid function and complications in adult male hypothyroid rats via upregulation of the L1 cell adhesion molecule.Thyroid research · 2024Article
- Thyroxine Levels Predict the Development of Brain Failure in Patients With Cirrhosis in Indian Population.Gastro hep advances · 2024Review
- Lower free triiodothyronine (fT3) levels in cirrhosis are linked to systemic inflammation, higher risk of acute-on-chronic liver failure, and mortality.JHEP reports : innovation in hepatology · 2024Article
- The Free Triiodothyronine, Gamma-Glutamyl Transpeptidase and Spontaneous Bacterial Peritonitis Index: A Novel Model for Predicting 1-Year Mortality in Patients with HBV-Related Hepatic Encephalopathy.Hepatic medicine : evidence and research · 2024Article
- Endocrinology for the hepatologist.Clinical liver disease · 2023Article
- Association of Thyroid Function and Severity of Illness in Liver Cirrhosis as Measured by Child-Pugh Score.Cureus · 2023Article
- Evolution of non-thyroidal illness syndrome in acute decompensation of liver cirrhosis and acute-on-chronic liver failure.Frontiers in endocrinology · 2023Article
- Vitamin E Prevented Hepatic and Renal Tissue Damage in Hypothyroid Rats.Advanced biomedical research · 2023Article
- Metformin and alpha lipoic acid ameliorate hypothyroidism and its complications in adult male rats.Journal of diabetes and metabolic disorders · 2022Article
- Transcriptome Profile of Thyroid Glands in Bile Duct Ligation Mouse Model.International journal of molecular sciences · 2022Article
- Development of a FT3-related prognostic model for patients with hepatitis B virus-related acute-on-chronic liver failure.Bioengineered · 2022Article
- [Research progress on the relationship between liver cirrhosis and thyroid hormones].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionLiver plays an important role in the metabolism of thyroid hormones, as it is the most important organ in the peripheral conversion of tetraiodothyronine (T4) to triiodothyronine (T3) by Type 1 deiodinase. MATERIALS AND
methodsThis case-control study included 100 decompensated liver cirrhosis patients (71 males and 29 females) and 100 apparently healthy controls (71 male and 29 female). Serum FT3, FT4, and thyroid-stimulating hormone (TSH) levels were measured using electrochemiluminescence immunoassay and analyses between cases versus healthy controls (Group 1) and further analyses in subgroups, cirrhosis with hepatic encephalopathy (HE) cases (
resultsMost common etiology was alcohol (46%) and presentation was gross ascites (74%). Cirrhosis patients had statistically significant lower level of FT3 (
conclusionThe mean FT3 and FT4 levels were significantly decrease and mean TSH levels were significantly increase in liver cirrhosis patients compared to healthy controls. Level of FT3, FT4, and TSH also correlate with the severity of liver disease, level of FT3 can be used as prognostic marker for liver cirrhosis patients.
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