Evidence map›Paper›PMID 30294553›Full record

ReviewJournal of clinical & translational endocrinology2018

Less known aspects of central hypothyroidism: Part 2 - Congenital etiologies.

Salvatore Benvenga, Marianne Klose, Roberto Vita, Ulla Feldt-Rasmussen

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical & translational endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Less known aspects of central hypothyroidism: Part 1 - Acquired etiologies.Journal of clinical & translational endocrinology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Salvatore BenvengaDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Marianne KloseDepartment of Medical Endocrinology and Metabolism, Rigshospitalet, National University Hospital, Copenhagen University, Copenhagen, Denmark.
Roberto VitaDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Ulla Feldt-RasmussenDepartment of Medical Endocrinology and Metabolism, Rigshospitalet, National University Hospital, Copenhagen University, Copenhagen, Denmark.
Copenhagen University Hospital · DKUniversity of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Central hypothyroidism (CH) occurs approximately in 1:50,000, and therefore is expected to be one thousand times rarer compared with primary hypothyroidism. Despite its rarity in the general population, it is much more common in certain disorders, in which it is frequently associated with other pituitary hormone deficiencies. The aim of this paper is to provide an updated review on the frequency of congenital CH, which is <1:50,000, and on its etiology, disregarding CH caused by other genetic defects, such as mutations of transcription factors involved in pituitary organogenesis or mutations of the genes encoding TRH or TRH receptor.

Indexed as

ACTH, adrenocorticotropin hormoneALGS, arteriohepatic dysplasiaCentral hypothyroidismCH, central hypothyroidismCongenital hypothyroidismDWS, Dandy-Walker syndromeFT3, free triiodothyronineFT4, free thyroxineGH, growth hormoneHCG, human chorionic gonadotropinHypopituitarismIGDF1, immunogobulin superfamily member 1PC1/3, proprotein convertase 1/3PWS, Prader-Willi syndromeROHHAD, rapid-onset obesity with hypoventilation, hypothalamic dysfunction and autonomic dysregulationSCD, sickle cell anemiaSMMCIS, solitary median maxillary central incisor syndromeSOD, septo-optic dysplasiaSWS, Sturge-Weber syndromeThyrotropin deficiencyTRH, TSH-releasing hormoneTSH, thyrotropinTT3, total triiodothyronineTT4, total thyroxine

Identifiers

PMID30294553
PMCPMC6171088
OpenAlexW2894050219

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.