Evidence map›Paper›PMID 30294470›Full record

ArticleStroke and vascular neurology2018

Registry report on prediction by Pocock cardiovascular score of cerebral microemboli acutely following carotid endarterectomy.

Mahmud Saedon, Athanasios Saratzis, Rachel W S Lee, Charles E Hutchinson, Christopher H E Imray, Donald R J Singer

Open access · goldAbstract read
In one paragraph

Article in Stroke and vascular neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Mahmud SaedonNottingham University Hospitals NHS Trust, Nottingham, UK.
Athanasios SaratzisLeicester Royal Infirmary, Leicester, UK.
Rachel W S LeeUniversity Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
Charles E HutchinsonUniversity Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
Christopher H E ImrayUniversity Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
Donald R J SingerYale School of Medicine, New Haven, Connecticut, USA.
University Hospitals Coventry and Warwickshire NHS Trust · GBLeicester Royal Infirmary · GBLondon Postgraduate Medical and Dental Education · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCerebral microemboli may lead to ischaemic neurological complications after carotid endarterectomy (CEA). The association between classical cardiovascular risk factors and acute cerebral microemboli following carotid surgery has not been studied. The aim of this study was to explore whether an established cardiovascular risk score (Pocock score) predicts the presence of cerebral microemboli acutely after CEA. SUBJECTS AND

methodsPocock scores were assessed for the 670 patients from the Carotid Surgery Registry (age 71±1 (SEM) years, 474 (71%) male, 652 (97%) Caucasian) managed from January 2002 to December 2012 in the Regional Vascular Centre at University Hospitals Coventry and Warwickshire NHS Trust, which serves a population of 950 000. CEA was undertaken in 474 (71%) patients for symptomatic carotid stenosis and in 196 (25%) asymptomatic patients during the same period. 74% of patients were hypertensive, 71% were smokers and 49% had hypercholesterolaemia.

resultsA high Pocock score (≥2.3%) was significantly associated with evidence of cerebral microemboli acutely following CEA (P=0.039, Mann-Whitney (MW) test). A Pocock score (≥2.3%) did not predict patients who required additional antiplatelet therapy (microemboli signal (MES) rate >50 hour

conclusionThese findings demonstrate that the Pocock score could be used as a clinical tool to identify patients at high risk of developing acute postoperative microemboli.

Indexed as

Decision Support TechniquesAgedCarotid StenosisClinical Decision-MakingEndarterectomy, CarotidFemaleHumansIntracranial EmbolismMalePredictive Value of TestsRegistriesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUltrasonography, Doppler, Transcranialcardiovascular risk factorscarotid endarterectomymicroembolipocock scoretranscranial doppler

Identifiers

PMID30294470
PMCPMC6169612
OpenAlexW2789428141

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.