ArticleAnnals of medicine and surgery (2012)2018
Gallbladder cancer in Eastern Province of Saudi Arabia: A retrospective cohort study.
Article in Annals of medicine and surgery (2012), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Adenocarcinoma of the gallbladder: an incidental histopathological finding post-operative laparoscopic cholecystectomy in Saudi Arabia.Journal of medicine and life · 2025Article
- Global trends in gallbladder cancer survival: A 30-year analysis of cancer registry data.Heliyon · 2025Review
- Update on Prevalence of Pain in Patients with Cancer 2022: A Systematic Literature Review and Meta-Analysis.Cancers · 2023Review
- Gallbladder cancer of two histological origins: A case report and review of literature.International journal of surgery case reports · 2021Article
- Unexpected histopathology results following routine examination of cholecystectomy specimens: How big and how significant?Annals of medicine and surgery (2012) · 2020Article
- Epidemiology of Gallbladder Cancer in Saudi Arabia.Cancer management and research · 2020Article
- Article
- Gallbladder cancer: 7-Year experience from Qatar.Annals of medicine and surgery (2012) · 2019Article
- Surgical outcomes of primary carcinosarcoma of the gallbladder after curative resection: A rare case series.International journal of surgery case reports · 2019Article
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6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is paucity in the literature regarding gallbladder cancer in Saudi Arabia, possibly because it is not among the top 10 cancers diagnosed nationwide according to the Saudi Cancer Registry. Moreover, national or regional data on gallbladder cancer in Saudi Arabia have not been analyzed. The purpose of this study was to describe the presentation, disease stage, histology, and survival rates for gallbladder cancer in Saudi patients at a single institution between January 1, 2010 and December 31, 2017. MATERIALS AND
methodsThis was a retrospective study of 76 patients who presented to our hospital between January 1, 2010 and December 31, 2017, with established diagnosis of gallbladder carcinoma. The diagnosis was made either histopathologically following simple laparoscopic cholecystectomy or biopsy from metastatic liver lesion in patients with gallbladder mass, or the high suspicion of gallbladder carcinoma based on incidental radiological findings. Presentation, disease stage, histology, and treatment modalities were analyzed using descriptive statistics and frequency distributions. Survival rates were analyzed and presented using Kaplan-Meier curves.
resultsBased on initial analyses the disease was more frequent among women (62.0%) than men (39.0%). Surgical resection was attempted in 40.8% patients. The average age at presentation and diagnosis of gallbladder carcinoma was 62.4 years. The disease had two peaks, one at 51.0 years and the other between 66.0 and 70.0 years. The median survival time for the overall at-risk patients was only 1.0 year, while for stage IVB patients was 7.2 months. Adenocarcinoma not otherwise specified (NOS) was the most common histopathology type (75.0%), with most patients presenting with stage IVB disease (75.0%). Gallbladder carcinoma was incidentally detected in 42.1%, including three cases (3.9%) diagnosed at our hospital.
conclusionsGallbladder cancer is a rare type of cancer in Saudi Arabia, and most patients are treated surgically, despite being mostly diagnosed at the advanced stage of the disease.
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