Evidence map›Paper›PMID 30294422›Full record

ArticleRSC advances2018

Hyaluronic acid hydrogel scaffolds loaded with cationic niosomes for efficient non-viral gene delivery.

Ilia Villate-Beitia, Norman F Truong, Idoia Gallego, Jon Zárate, Gustavo Puras, José Luis Pedraz, Tatiana Segura

Abstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Gene Delivery From Granular Scaffolds for Tunable Biologics Manufacturing.Small (Weinheim an der Bergstrasse, Germany) · 2024
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Nucleic Acid Delivery from Granular Hydrogels.Advanced healthcare materials · 2022
    Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ilia Villate-BeitiaNanoBioCel Group, School of Pharmacy, University of the Basque Country (UPV/EHU), 01006 Vitoria-Gasteiz, Spain. Email: joseluis.pedraz@ehu.eus.
Norman F TruongDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095, USA. Email: tatiana.segura@duke.edu.
Idoia GallegoNanoBioCel Group, School of Pharmacy, University of the Basque Country (UPV/EHU), 01006 Vitoria-Gasteiz, Spain. Email: joseluis.pedraz@ehu.eus.
Jon ZárateNanoBioCel Group, School of Pharmacy, University of the Basque Country (UPV/EHU), 01006 Vitoria-Gasteiz, Spain. Email: joseluis.pedraz@ehu.eus.
Gustavo PurasNanoBioCel Group, School of Pharmacy, University of the Basque Country (UPV/EHU), 01006 Vitoria-Gasteiz, Spain. Email: joseluis.pedraz@ehu.eus.
José Luis PedrazNanoBioCel Group, School of Pharmacy, University of the Basque Country (UPV/EHU), 01006 Vitoria-Gasteiz, Spain. Email: joseluis.pedraz@ehu.eus.ORCID 0000-0002-3938-2267
Tatiana SeguraDepartment of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA 90095, USA. Email: tatiana.segura@duke.edu.

Funding

Hydrogels for Local Gene Delivery and Therapeutic AngiogenesisR01HL110592 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SEGURA, TATIANA · 2011 to 2015
$1.8M
NHLBI NIH HHS R01 HL110592
6 · The paper itself

Abstract

The lack of ideal non-viral gene carriers has motivated the combination of delivery systems and tissue-engineered scaffolds, which may offer relevant advantages such as enhanced stability and reduced toxicity. In this work, we evaluated a new combination between niosome non-viral vectors and hyaluronic acid (HA) hydrogel scaffolds, both widely studied due to their biocompatibility as well as their ability to incorporate a wide variety of molecules. We evaluated three different niosome formulations (niosomes

Identifiers

PMID30294422
PMCPMC6146377

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.