Evidence map›Paper›PMID 30294271›Full record

ArticleFrontiers in pharmacology2018

Identification of Antioxidant Proteins With Deep Learning From Sequence Information.

Lifen Shao, Hui Gao, Zhen Liu, Juan Feng, Lixia Tang, Hao Lin

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Predicting antioxidant activity of compounds based on chemical structure using machine learning methods.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2024
    Article
  2. Article
  3. ANPrAod: Identify Antioxidant Proteins by Fusing Amino Acid Clustering Strategy andComputational and mathematical methods in medicine · 2021
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lifen ShaoCenter for Informational Biology, School of Computer Science and Engineering, University of Electronic Science and Technology of China, Chengdu, China.
Hui GaoCenter for Informational Biology, School of Computer Science and Engineering, University of Electronic Science and Technology of China, Chengdu, China.
Zhen LiuCenter for Informational Biology, School of Computer Science and Engineering, University of Electronic Science and Technology of China, Chengdu, China.
Juan FengKey Laboratory for Neuro-Information of Ministry of Education, Center for Informational Biology, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China.
Lixia TangKey Laboratory for Neuro-Information of Ministry of Education, Center for Informational Biology, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China.
Hao LinKey Laboratory for Neuro-Information of Ministry of Education, Center for Informational Biology, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China.
University of Electronic Science and Technology of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antioxidant proteins have been found closely linked to disease control for its ability to eliminate excess free radicals. Because of its medicinal value, the study of identifying antioxidant proteins is on the upsurge. Many machine-learning classifiers have performed poorly owing to the nonlinear and unbalanced nature of biological data. Recently, deep learning techniques showed advantages over many state-of-the-art machine learning methods in various fields. In this study, a deep learning based classifier was proposed to identify antioxidant proteins based on mixed g-gap dipeptide composition feature vector. The classifier employed deep autoencoder to extract nonlinear representation from raw input. The t-Distributed Stochastic Neighbor Embedding (t-SNE) was used for dimensionality reduction. Support vector machine was finally performed for classification. The classifier achieved

Indexed as

antioxidant proteinsdeep learningfeature selectiong-gap dipeptidewebserver

Identifiers

PMID30294271
PMCPMC6158654
OpenAlexW2890201337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.