Evidence map›Paper›PMID 30294263›Full record

ArticleFrontiers in systems neuroscience2018

A Comparison of Machine Learning Classifiers for Energy-Efficient Implementation of Seizure Detection.

Farrokh Manzouri, Simon Heller, Matthias Dümpelmann, Peter Woias, Andreas Schulze-Bonhage

Open access · goldAbstract read
In one paragraph

Article in Frontiers in systems neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Farrokh ManzouriEpilepsy Center, Faculty of Medicine, University of Freiburg Medical Center, Freiburg, Germany.
Simon HellerBrainLinks-BrainTools Cluster of Excellence, University of Freiburg, Freiburg, Germany.
Matthias DümpelmannEpilepsy Center, Faculty of Medicine, University of Freiburg Medical Center, Freiburg, Germany.
Peter WoiasBrainLinks-BrainTools Cluster of Excellence, University of Freiburg, Freiburg, Germany.
Andreas Schulze-BonhageEpilepsy Center, Faculty of Medicine, University of Freiburg Medical Center, Freiburg, Germany.
Brain (Germany) · DEUniversity of Freiburg · DEBernstein Center for Computational Neuroscience Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The closed-loop application of electrical stimulation via chronically implanted electrodes is a novel approach to stop seizures in patients with focal-onset epilepsy. To this end, an energy efficient seizure detector that can be implemented in an implantable device is of crucial importance. In this study, we first evaluated the performance of two machine learning algorithms (Random Forest classifier and support vector machine (SVM)) by using selected time and frequency domain features with a limited need of computational resources. Performance of the algorithms was further compared to a detection strategy implemented in an existing closed loop neurostimulation device for the treatment of epilepsy. The results show a superior performance of the Random Forest classifier compared to the SVM classifier and the reference approach. Next, we implemented the feature extraction and classification process of the Random Forest classifier on a microcontroller to evaluate the energy efficiency of this seizure detector. In conclusion, the feature set in combination with Random Forest classifier is an energy efficient hardware implementation that shows an improvement of detection sensitivity and specificity compared to the presently available closed-loop intervention in epilepsy while preserving a low detection delay.

Indexed as

closed-loop interventionepilepsyintracranial EEGlow power microcontroller implementationmachine learningseizure detection

Identifiers

PMID30294263
PMCPMC6158331
OpenAlexW2891604564

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.