ReviewFrontiers in molecular neuroscience2018
Gadolinium Deposition in Brain: Current Scientific Evidence and Future Perspectives.
Review in Frontiers in molecular neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
107 citing papers in PubMed, 1 synthesis or guideline pooled it, 222 citations in OpenAlex.
- Magnetic Resonance Imaging for the diagnosis and management of acute colonic diverticulitis: a review of current and future use.Journal of medical radiation sciences · 2021Pooled it
- Improved Detection of Bone Metastases in Children and Young Adults with Ferumoxytol-enhanced MRI.Radiology. Imaging cancer · 2023Trial
- Concurrent Four-Dimensional Dynamic MRA and Perfusion Imaging Using Dual-Module Arterial Spin Labeling MRI With Stack-Of-Stars Golden-Angle Radial Acquisition.NMR in biomedicine · 2026Article
- Design and characterization of in situ cell-penetrating multi-modal gadolinium-gold nanoparticles for MR and CT imaging.Biomaterials · 2026Article
- Magnetite nanodiscs as vortex-enhanced MRI contrast agents: a novel approach in medical imaging.Nanoscale advances · 2026Article
- Acute susceptibility changes of deep gray matter nuclei to gadobutrol: a prospective longitudinal study using quantitative susceptibility mapping.Quantitative imaging in medicine and surgery · 2026Article
- Utilizing post-imaging surveys to guide development of photoacoustic computed technology for breast imaging.American journal of surgery · 2026Article
- Cerebral Accumulation of Gadolinium (GdTomography (Ann Arbor, Mich.) · 2026Article
- Effect of distributing urine-collection bags on contrast-material load in wastewater.European radiology · 2026Observational
- Usability of Amorphous Manganese Oxide for Assessing the Proteoglycan Content in Articular Cartilage.Magnetic resonance in chemistry : MRC · 2026Article
- Clinical Evaluation of Susceptibility-weighted MR Imaging for the Detection of Intramammary Micro- and Macrocalcifications in 70 Female Patients at 1.5T.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026Article
- MR-Guidance of Gene Therapy for Brain Diseases: Moving From Palliative Treatment to Cures.Journal of magnetic resonance imaging : JMRI · 2025Review
- Simultaneous TMagnetic resonance in medicine · 2025Article
- Gadolinium toxicity: mechanisms, clinical manifestations, and nanoparticle role.Archives of toxicology · 2025Review
- In-vitro Detection of Intramammary-like Macrocalcifications Using Susceptibility-weighted MR Imaging Techniques at 1.5T.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025Article
- Rotating Frame Relaxation Time Mapping for the Visualization of the Sinoatrial Node Without Contrast Agent.NMR in biomedicine · 2025Article
- How useful is contrast-enhanced MRI in the long-term surveillance of glioma? A multicentre retrospective longitudinal cohort study.European radiology · 2025Article
- Investigating the Role of Intravoxel Incoherent Motion Diffusion-Weighted Imaging in Evaluating Multiple Sclerosis Lesions.Diagnostics (Basel, Switzerland) · 2025Article
- Characterizing the evolution of lesion, penumbra and blood-brain barrier permeability in a photothrombotic juvenile rat stroke model using MRI and histology.Scientific reports · 2025Article
- Contrast Agents in Breast MRI: State of the Art and Future Perspectives.Biomedicines · 2025Review
47 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the past 4 years, many publications described a concentration-dependent deposition of gadolinium in the brain both in adults and children, seen as high signal intensities in the globus pallidus and dentate nucleus on unenhanced T1-weighted images. Postmortem human or animal studies have validated gadolinium deposition in these T1-hyperintensity areas, raising new concerns on the safety of gadolinium-based contrast agents (GBCAs). Residual gadolinium is deposited not only in brain, but also in extracranial tissues such as liver, skin, and bone. This review summarizes the current evidence on gadolinium deposition in the human and animal bodies, evaluates the effects of different types of GBCAs on the gadolinium deposition, introduces the possible entrance or clearance mechanism of the gadolinium and potential side effects that may be related to the gadolinium deposition on human or animals, and puts forward some suggestions for further research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.