ArticleThe Egyptian journal of neurology, psychiatry and neurosurgery2018
The relationship between the severity of disability and serum IL-8 in acute ischemic stroke patients.
Article in The Egyptian journal of neurology, psychiatry and neurosurgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 19 citations in OpenAlex.
- Functional improvement and immune-inflammatory cytokines profile of ischaemic stroke patients after treatment with boswellic acids: a randomized, double-blind, placebo-controlled, pilot trial.Inflammopharmacology · 2019Trial
- Thrombin Generation Capacity is Associated With Worse Outcome in r-tPA Treated Patients With Stroke.Translational stroke research · 2026Article
- The Impact of Post-Stroke Disability on Rehabilitation Costs in Romania.Journal of clinical medicine · 2025Article
- Systemic Inflammation at the Crossroad of Major Depressive Disorder and Comorbidities: A Narrative Review.International journal of molecular sciences · 2025Review
- Salivary chemokines and growth factors in patients with ischemic stroke.Scientific reports · 2025Article
- Plasma Proteomes and Genome-Wide Association Data for Causal Protein Identification in Stroke.Molecular neurobiology · 2025Article
- The role of inflammation in Ischemic stroke: from biomarker to treatment.Frontiers in immunology · 2025Review
- Effects of peripheral blood cells on ischemic stroke: Greater immune response or systemic inflammation?Heliyon · 2024Review
- IL-8 (CXCL8) Correlations with Psychoneuroimmunological Processes and Neuropsychiatric Conditions.Journal of personalized medicine · 2024Review
- Blood biomarker changes following therapeutic hypothermia in ischemic stroke.Brain and behavior · 2023Article
- Interleukins and Ischemic Stroke.Frontiers in immunology · 2022Review
- Contrasting Roles of Ang II and ACEA in the Regulation of IL10 and IL1β Gene Expression in Primary SHR Astroglial Cultures.Molecules (Basel, Switzerland) · 2021Article
- Bioinformatics Analysis of Gene Expression Profiles of Sex Differences in Ischemic Stroke.BioMed research international · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStroke is the third leading cause of death and leading cause of adult disability worldwide. Long-term disability is a significant problem among survivors; post-stroke inflammation is well known to contribute to the expansion of the ischemic lesion resulting in significant morbidity and disability. To study the impact of serum level of IL-8 on severity of disability in patients with acute ischemic stroke in the first 48 h post stroke.
methodsA cross-sectional case control study was conducted on 44 patients with acute ischemic stroke (in the first 48 h). The patients were subjected to full neurological examination, computed tomography (CT) and magnetic resonance imaging (MRI) of the brain, and assessment of stroke disability using the National Institute of Health Stroke Scale (NIHSS) and modified Rankin Scale (mRS). Measurement of the serum levels of IL-8, erythrocyte sedimentation rate, and C-reactive protein (CRP) was done. Forty-four matched control subjects for their age and sex were included for comparison of serum level of IL-8.
resultsThe level of IL-8 was significantly higher in the patients than in the control subjects (
conclusionThe severity of disability in early acute ischemic stroke is highly correlated to the serum level of IL-8.
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