ArticleContemporary clinical dentistry2018
Dental Caries Experience, Dental Anomalies, and Morphometric Analysis of Canine among Monozygotic and Dizygotic Twins.
Article in Contemporary clinical dentistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Heritability of dental arches and occlusal characteristics: a systematic review and meta-analysis.European journal of orthodontics · 2023Pooled it
- Article
- Longitudinal Study of Oral Microbiome Variation in Twins.Scientific reports · 2020Article
- A study on genetic and mutans streptococcal transmissibility of dental caries.Journal of oral and maxillofacial pathology : JOMFPArticle
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe study of twins is a well-known and a unique method that is used to investigate the genetic contributions to physical features and diseases in human.
aimTo estimate the relative contributions of genetic and environmental influence to observed variations in different dental features or traits. METHODOLOGY: Thirty twins in the age group of 15-30 years were selected for the study, and the dental caries experience scores, dental anomalies, and morphometric analysis of monozygotic (MZ) and dizygotic (DZ) twins were compared.
resultsMZ twins unlike DZ twins showed within-pair resemblance in decayed, decayed missing and filled teeth (DMFT), and molar relation. No morphometric analysis parameters and dental anomalies had significant mean difference between the groups. Decay, filling, DMFT, spacing, mandibular irregularity, open bite, and mesiodistal width of the right and left canine showed a higher positive correlation in MZ than DZ twins. Heritability estimate was low for morphometric analysis parameters. There is genetic dominance in decay, DMFT, spacing, molar relation, and diastema. Pearson's correlation revealed a positive and statistically significant correlation among all morphometric analysis parameters for MZ twins, but not DZ twins. Dental caries has a higher concordance rate (87.5%), correlation (71.6%), and heritability (87.8%).
conclusionMost of the dental parameters are significantly heritable with up to 85% of the variance attributable to genetic factors. Environmental factors play a major role in developing malocclusion and causing dental caries. Morphology of canines can be used as a supplementary tool to determine zygosity.
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