Evidence map›Paper›PMID 30294146›Full record

ArticleContemporary clinical dentistry2018

Evaluation of Serum Leptin and Adiponectin in Obese Individuals with Chronic Periodontitis.

Ramanarayana Boyapati, Srikanth Chintalapani, Arpita Ramisetti, Shyam Sunder Salavadhi, Radhika Ramachandran

Open access · goldAbstract read
In one paragraph

Article in Contemporary clinical dentistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ramanarayana BoyapatiDepartment of Periodontics, Mamata Dental College, Khammam, Telangana, India.
Srikanth ChintalapaniDepartment of Periodontics, Mamata Dental College, Khammam, Telangana, India.
Arpita RamisettiDepartment of Periodontics, Mamata Dental College, Khammam, Telangana, India.
Shyam Sunder SalavadhiDepartment of Periodontics, Mamata Dental College, Khammam, Telangana, India.
Radhika RamachandranDepartment of Periodontics, Mamata Dental College, Khammam, Telangana, India.
Mamata Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesStudies have reported changes in leptin and adiponectin levels in the gingival crevicular fluid, saliva, and blood serum of obese patients with periodontal disease. The aim of the study is to evaluate serum leptin and adiponectin levels in obese and nonobese individuals with chronic periodontitis and to deduce a relationship between the clinical parameters and the inflammatory biochemical parameters. MATERIALS AND

methodsIn this case-control study, a total of fifty individuals were selected based on the body mass index (BMI): Group I of obese individuals with chronic periodontitis and Group II of nonobese individuals with chronic periodontitis. Periodontal parameters used in this study were plaque index, gingival index, probing pocket depth, and clinical attachment level. The effects of obesity and periodontal status on serum leptin and adiponectin levels of both groups were statistically analyzed using an independent t- test.

resultsStatistical analysis showed that the effect of BMI on serum leptin and adiponectin levels was statistically significant (

conclusionsIn obese individuals with chronic periodontitis, serum leptin levels were significantly high compared to nonobese individuals and serum adiponectin levels were significantly lower in obese individuals compared to nonobese individuals with periodontitis, though both the parameters were independent of each other.

Indexed as

Adiponectinchronic periodontitisenzyme-linked immunosorbent assayleptinobesity

Identifiers

PMID30294146
PMCPMC6169280
OpenAlexW2890607989

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.