ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2018
Non- Neurological Complications after Traumatic Brain Injury: A Prospective Observational Study.
Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 37 citations in OpenAlex.
- Brain-kidney cross-talk: A call for action!World journal of critical care medicine · 2026Article
- Mesenchymal stem cell transplantation alleviated TBI-induced lung injury by inhibiting PAD4-dependent NET formation.Journal of advanced research · 2026Article
- From brain to body: sinapic acid prevents multi-organ damage post-traumatic brain injury in mice.Metabolic brain disease · 2026Article
- Acute kidney injury in critically ill patients with traumatic brain injury: A single-center retrospective cohort study.World journal of critical care medicine · 2025Article
- C-reactive protein to albumin ratio and Glasgow Coma Scale score as the predictors for weaning outcomes in traumatic brain injury.Annals of medicine · 2025Article
- Neurogenic organ dysfunction syndrome after acute brain injury.Military Medical Research · 2025Review
- Epidemiology of Neurotrauma in Pediatric Intensive Care Unit: A Single-center Experience of 10 Years.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025Article
- Roles and therapeutic potential of different extracellular vesicle subtypes on traumatic brain injury.Cell communication and signaling : CCS · 2023Review
- Functional outcome in patients with traumatic or hemorrhagic brain injuries undergoing decompressive craniectomy versus craniotomy and 6-month rehabilitation.Scientific reports · 2023Observational
- Association of hyperchloremia and acute kidney injury in pediatric patients with moderate and severe traumatic brain injury.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
- Brain-lung interactions and mechanical ventilation in patients with isolated brain injury.Critical care (London, England) · 2021Review
- Links between thrombosis and inflammation in traumatic brain injury.Thrombosis research · 2021Review
- Challenges of Delirium Management in Patients with Traumatic Brain Injury: From Pathophysiology to Clinical Practice.Current neuropharmacology · 2021Review
- The predictive value of RDW in AKI and mortality in patients with traumatic brain injury.Journal of clinical laboratory analysis · 2020Article
- The Predictive Value of Serum Uric Acid on Acute Kidney Injury following Traumatic Brain Injury.BioMed research international · 2020Article
- Risk factors of deterioration in patients of head injury with non-operative management on first neurosurgical consultation.Journal of neurosciences in rural practiceArticle
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
INTRODUCTION AND
aimsRecognizing and treating nonneurological complications occurring in traumatic brain injury (TBI) patients during intensive care unit (ICU) stay are challenging. The aim is to estimate various nonneurological complications in TBI patients. The secondary aim is to see the effect of these complications on ICU stay, disability, and mortality. MATERIALS AND
methodsThis was a prospective observational study at the neuro-ICU of a Level-I trauma center. A total of 154 TBI patients were enrolled. The period of the study was from admission to discharge from ICU or demise. Inclusion criteria were patients aged >16 years and patients with severe TBI (Glasgow coma score [GCS] ≤8). Nonneurological complications were frequent in TBI patients.
resultsWe observed respiratory complications to be the most common (61%). Other complications, in the decreasing order, included dyselectrolytemia (46.1%), cardiovascular (34.4%), coagulopathy (33.1%), sepsis (26%), abdominal complications (17.5%), and acute kidney injury (AKI, 3.9%). The presence of systemic complications except AKI was found to be significantly associated with increased ICU stay. Most of the patients of AKI died early in ICU. Respiratory dysfunction was found to be independently associated with 3.05 times higher risk of worsening clinical condition (disability) (
conclusionTBI patients tend to have poor outcome due to concomitant nonneurological complications. These have significant bearing on ICU stay, disability, and mortality.
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