ArticleJournal of dispersion science and technology2018
Investigation of Chiral Recognition by Molecular Micelles with Molecular Dynamics Simulations.
Article in Journal of dispersion science and technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Recognition Mechanisms of Chiral Selectors: An Overview.Methods in molecular biology (Clifton, N.J.) · 2026Review
- Past, present, and future developments in enantioselective analysis using capillary electromigration techniques.Electrophoresis · 2021Review
- Characterization of Amino Acid Based Molecular Micelles with Molecular Modeling.Open journal of physical chemistry · 2019Article
- Chiral Selectors in Capillary Electrophoresis: Trends During 2017⁻2018.Molecules (Basel, Switzerland) · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Molecular dynamics simulations were used to characterize the binding of the chiral drugs chlorthalidone and lorazepam to the molecular micelle poly-(sodium undecyl-(L)-leucine-valine). The project's goal was to characterize the nature of chiral recognition in capillary electrophoresis separations that use molecular micelles as the chiral selector. The shapes and charge distributions of the chiral molecules investigated, their orientations within the molecular micelle chiral binding pockets, and the formation of stereoselective intermolecular hydrogen bonds with the molecular micelle were all found to play key roles in determining where and how lorazepam and chlorthalidone enantiomers interacted with the molecular micelle.
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Registered trials
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