Evidence map›Paper›PMID 30293217›Full record

ArticleInternational journal of hematology2019

Massive bone marrow necrosis revealing an HIV-related primary bone marrow lymphoma: a diagnostic challenge.

Michael D Diamantidis, Vasiliki Gogou, Triantafyllia Koletsa, Simeon Metallidis, Maria Papaioannou

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In one paragraph

Article in International journal of hematology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Michael D DiamantidisDepartment of Haematology, First Department of Internal Medicine, Faculty of Medicine, AHEPA General Hospital, Aristotle University of Thessaloniki (AUTH), S. Kiriakidi St. 1, 54 636, Thessaloniki, Greece.
Vasiliki GogouDepartment of Haematology, First Department of Internal Medicine, Faculty of Medicine, AHEPA General Hospital, Aristotle University of Thessaloniki (AUTH), S. Kiriakidi St. 1, 54 636, Thessaloniki, Greece.
Triantafyllia KoletsaDepartment of Pathology, Faculty of Medicine, AHEPA General Hospital, Aristotle University of Thessaloniki (AUTH), S. Kiriakidi St. 1, 54 636, Thessaloniki, Greece.
Simeon MetallidisDepartment of Haematology, First Department of Internal Medicine, Faculty of Medicine, AHEPA General Hospital, Aristotle University of Thessaloniki (AUTH), S. Kiriakidi St. 1, 54 636, Thessaloniki, Greece.
Maria PapaioannouDepartment of Haematology, First Department of Internal Medicine, Faculty of Medicine, AHEPA General Hospital, Aristotle University of Thessaloniki (AUTH), S. Kiriakidi St. 1, 54 636, Thessaloniki, Greece. marygpap@gmail.com.ORCID http://orcid.org/0000-0002-1999-9622
Aristotle University of Thessaloniki · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone marrow necrosis (BMN) is a condition that can be difficult to diagnose, requiring a hematologist experienced in bone marrow morphology. This diagnostic challenge should alert the clinician of a severe disease or a possible underlying malignancy, either hematological or a solid tumor. We describe the concomitant presence of a primary bone marrow lymphoma (diffuse large B-cell lymphoma-DLBCL), along with an extensive BMN in an HIV patient for the first time in a living individual. HIV infection, BMN and DLBCL presented a multifactorial crossword of molecular events underlying the complex pathophysiology. The exact precipitating pathophysiological events resulting in BMN remain obscure and provide their clear impact for future research. The present report is instructive and also contains a critical review of the literature related to the case presented.

Indexed as

HIVNecrosisBone MarrowBone Marrow DiseasesBone Marrow NeoplasmsHumansLymphoma, Large B-Cell, DiffusePrognosisBone marrow necrosis (BMN)Diffuse large B-cell lymphoma (DLBCL)Dismal prognosisHuman immunodeficiency virus (HIV)Primary bone marrow lymphoma

Identifiers

PMID30293217
OpenAlexW2895541383

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.