SynthesisDigestive diseases and sciences2019
Periampullary Diverticula and ERCP Outcomes: A Systematic Review and Meta-Analysis.
Synthesis in Digestive diseases and sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Does periampullary diverticulum affect ERCP cannulation and post-procedure complications? an up-to-date meta-analysis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2020Pooled it
- Endoscopic sphincterotomy with balloon dilation vs. monotherapy for choledocholithiasis in periampullary diverticulum: a randomized trial.Scientific reports · 2025Trial
- The role of preoperative antibiotic prophylaxis in the relationship between intestinal colonization and post-ERCP biliary tract infection: a prospective cohort study.Antimicrobial resistance and infection control · 2026Article
- Risk Factors for Post-ERCP Pancreatitis: Impact of Transpancreatic Septotomy, Needle-Knife Precut, and Duodenal Diverticulum in 1226 Procedures.Journal of clinical medicine · 2026Article
- Bleeding From a Lateral Duodenal Diverticulum Complicated by a Retroperitoneal Perforation After Endoscopic Clipping.Case reports in gastrointestinal medicine · 2026Article
- Impact of Papillary Morphology and Diverticular Type on Needle-Knife Papillotomy in Patients with Periampullary Diverticulum with Difficult Biliary Cannulation.Journal of clinical medicine · 2025Article
- Endoscopic retrograde cholangiopancreatography in elderly patients: Is age just a number or something more?World journal of gastroenterology · 2025Article
- Impact of periampullary diverticulum and relevant cannulation techniques on the outcomes of endoscopic retrograde cholangiopancreatography: a retrospective study.BMC gastroenterology · 2025Article
- Is endoscopic retrograde cholangiopancreatography a reliable procedure in advanced age? A single tertiary center experience.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025Article
- A Challenging Case of Endoscopic Retrograde Cholangiopancreatography Due to an Intradiverticular Papilla.Cureus · 2025Article
- Association of periampullary diverticulum types with post-ERCP hyperamylasemia: a retrospective observational study.BMC gastroenterology · 2025Observational
- The assessment of postoperative cholangitis in malignant biliary obstruction: a real-world study of nasobiliary drainage after endoscopic placement of self-expandable metal stent.Frontiers in oncology · 2024Article
- The impact of periampullary diverticula on cannulation and adverse events in endoscopic retrograde cholangiopancreatography.Therapeutic advances in gastroenterology · 2024Article
- Impact of periampullary diverticulum on endoscopic retrograde cholangiopancreatography: bridging the gap between fiction and reality.Przeglad gastroenterologiczny · 2024Article
- A new classification of periampullary diverticulum: cannulation of papilla on the inner margins of the diverticulum (Type IIa) is more challenging.BMC gastroenterology · 2023Article
- [Acute cholangitis secondary to periampullary duodenal diverticulum. Case report].Revista medica del Instituto Mexicano del Seguro Social · 2023Article
- Article
- Peri-ampullary diverticulum was associated with a higher rate of acute cholangitis among patients with choledocholithiasis.Surgical endoscopy · 2022Article
- Analysis of Risk Factors in Endoscopic Retrograde Cholangiopancreatography-Related Immediate and Delayed Hemorrhage.Digestive diseases and sciences · 2021Article
- Radial sphincterotomy in endoscopic retrograde cholangiopancreatography due to extrahepatic obstructions by large stones in the common bile duct.Fujita medical journal · 2021Article
Corrections and comments
- Commented on by
Authors and funding
8 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPeriampullary diverticulum (PAD) is most often asymptomatically found in elderly population. ERCP in the presence of PAD is technically challenging since the location and orientation of the ampulla could be altered. Various studies have reported differing results on the technical success and safety outcomes of ERCP in the presence of PAD. We aimed at a meta-analysis of such studies to assess the technical success and the occurrence of complications during ERCP in patients with PAD.
methodsWe conducted a comprehensive search of several databases and conference proceedings including PubMed, EMBASE, and Web of Science databases (earliest inception to October 2017). The search was done in accordance with PRISMA guidelines to identify studies. Studies that reported on the ERCP outcomes based on the presence of PAD were included. Both prospective and retrospective studies, manuscripts and abstracts were included. Only articles in English literature were included. The primary analysis focused on the overall technical success of ERCP in the presence of PAD, and the secondary analysis was to estimate the risk of occurrence of complications.
resultsOur search resulted in 16 studies that were included for final analysis. These 16 studies reported on 2794 patients, who had PAD, and the control group included 13,032 patients, who did not have a PAD during ERCP. Our meta-analysis of this data showed an Odd's ratio estimate of having a successful ERCP procedure in patients with PAD to be 0.51 [95% C.I. (0.35-0.72)] when compared to patients without it. This was statistically significant, with a p value 0.00. Considerable heterogeneity was noted among the studies. The heterogeneity proportion was quantified at 74.6% based on I
conclusionERCP is technically feasible and increasingly successful when performed by experts in the presence of PAD. The risk of complications such as PEP, bleeding, perforation and cholangitis does not differ between ERCP done in patients with and without PAD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.