ArticleMikrochimica acta2018
Fluorometric determination of doxycycline based on the use of carbon quantum dots incorporated into a molecularly imprinted polymer.
Article in Mikrochimica acta, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 86 citations in OpenAlex.
- Rhodamine B-assisted fluorescent aptasensor for the sensitive and selective assessment of Doxycycline hyclate in wastewater.Scientific reports · 2026Article
- Deep eutectic solvent-based magnetic molecular nanomaterials coupled with fluorescent carbon dots as a new strategy to highly enrich and sensitively detect doxycycline in food matrices.Food chemistry: X · 2025Article
- Detection of Doxycycline Using Carbon Quantum dots as Probe Based on Internal Filtering Effect.Journal of fluorescence · 2024Article
- Electrochemical determination of ascorbic acid using palladium supported on N-doped graphene quantum dot modified electrode.Scientific reports · 2024Article
- Encapsulating functionalized graphene quantum dot into metal-organic framework as a ratiometric fluorescent nanoprobe for doxycycline sensing.Mikrochimica acta · 2023Article
- Green ecofriendly electrochemical sensing platform for the sensitive determination of doxycycline.Heliyon · 2023Article
- A Novel Quantum Dots-Based Fluorescent Sensor for Determination of the Anticancer Dacomitinib: Application to Dosage Forms.Molecules (Basel, Switzerland) · 2023Article
- Advances and Challenges of Fluorescent Nanomaterials for Synthesis and Biomedical Applications.Nanoscale research letters · 2021Review
- One-step synthesis of N, S-doped carbon dots with orange emission and their application in tetracycline antibiotics, quercetin sensing, and cell imaging.Mikrochimica acta · 2021Article
- Eco-friendly ionic liquid imprinted polymer based on a green synthesis strategy for highly selective adsorption tylosin in animal muscle samples.Environmental science and pollution research international · 2021Article
- An eco-friendly imprinted polymer based on graphene quantum dots for fluorescent detection ofRSC advances · 2019Article
- A turn-on fluorescent sulfide probe prepared from carbon dots and MnOMikrochimica acta · 2019Article
- A fluorescent nanoprobe for 4-ethylguaiacol based on the use of a molecularly imprinted polymer doped with a covalent organic framework grafted onto carbon nanodots.Mikrochimica acta · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
A fluorometric assay is described for doxycycline detection. It is based on the use of nitrogen-doped carbon quantum dots (NCQDs) coated with molecularly imprinted polymers (MIPs). The NCQDs were prepared by a one-step hydrothermal reaction using citric acid and ethylenediamine (EDA) as the starting materials. Afterwards, the NCQDs were incorporated into the polymer that was molecularly imprinted with doxycycline. It is found that doxycycline quenches the fluorescence of the NCQDs, and that the functional groups on the surface of NCQDs play an important role in terms of quenching efficiency. A larger fraction of carboxyl groups presented on the surface of NCQDs leads to a higher quenching efficiency due to the enhanced electron transfer from NCQD to doxycycline. The NCQDs@MIP composite can specifically and rapidly recognize doxycycline. Fluorescence drops linearly in the 5 to 50 μM doxycycline concentration range, and the limit of detection is 87 nM. This method was successfully applied to the determination of doxycycline in spiked pig serum where it gave recovery rates of >94%. Graphical abstract Schematic illustration for fabricating a fluorescent sensor based on nitrogen-doped carbon quantum dots (NCQDs) and molecularly imprinted polymers (MIPs). The sensor integrates the merits of the high sensitivity of NCQD and good selectivity of MIPs, and can be significantly quenched upon interaction with doxycycline.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.