Evidence map›Paper›PMID 30293141›Full record

ArticleInternational orthopaedics2019

Total knee arthroplasty in Italy: reflections from the last fifteen years and projections for the next thirty.

Emilio Romanini, Francesco Decarolis, Ilaria Luzi, Gustavo Zanoli, Michele Venosa, Paola Laricchiuta, Eugenio Carrani, Marina Torre

3 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in International orthopaedics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05563155 phase4completednot on this mapstarted 2021, after this paper: background citation

Repeat Dose Steroid to Prevent Pain Relapse After Total Knee Arthroplasty in Patients With High Pain Response - A Randomized Double-blind Placebo-controlled Trial

TypeinterventionalSponsorVejle HospitalRan2021 to 2024Enrolled110ConditionsPost Operative Pain, AcuteArmsDexamethasone 24 mg, Placebo
NCT05668312 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Effects of Tele-prehabilitation on Clinical and Muscular Recover in Patients Waiting for Knee Replacement: a Randomized Controlled Trial

TypeinterventionalSponsorI.R.C.C.S Ospedale Galeazzi-Sant'AmbrogioRan2023 to 2025Enrolled68ConditionsKnee OsteoarthritisArmsTele-prehabilitation, Standard prehabilitation
NCT06088602 naunknown statusnot on this mapstarted 2024, after this paper: background citation

The Effect of Cryoneurolysis for the Treatment of Acute Postoperative Pain Following Total Knee Arthroplasty in High Pain Responders - A Randomized, Participant- and Observer-masked, Sham-controlled Trial

TypeinterventionalSponsorCopenhagen University Hospital, HvidovreRan2024 to 2025Enrolled44ConditionsAcute Postoperative PainArmsCryoneurolysis, Sham
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  5. A Rare Case of Prosthetic Joint Infection Caused by Group DCase reports in infectious diseases · 2026
    Article
  6. Total hip arthroplasty in Italy: an observational, population-based study on surgical volume growth from 2001 to 2023 and forecasts until 2050 with six different statistical models.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Emilio RomaniniGLOBE, Italian Working Group on Evidence Based Orthopaedics, Rome, Italy. romanini@artrogruppo.it.ORCID http://orcid.org/0000-0002-3686-3137
Francesco DecarolisUniversità Bocconi, Milan, Italy.
Ilaria LuziNational Centre for Clinical Excellence, Safety and Quality of Care, Istituto Superiore di Sanità, Rome, Italy.
Gustavo ZanoliGLOBE, Italian Working Group on Evidence Based Orthopaedics, Rome, Italy.
Michele VenosaArtrogruppo, Casa di Cura San Feliciano, Rome, Italy.
Paola LaricchiutaNational Centre for Clinical Excellence, Safety and Quality of Care, Istituto Superiore di Sanità, Rome, Italy.
Eugenio CarraniNational Centre for Clinical Excellence, Safety and Quality of Care, Istituto Superiore di Sanità, Rome, Italy.
Marina TorreGLOBE, Italian Working Group on Evidence Based Orthopaedics, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAnnual rates of knee arthroplasty are increasing in all developed countries, imposing a significant economic and organizational burden; it is crucial to forecast the future need for knee arthroplasty, to assist stakeholders in planning strategies and investments, especially in a country like Italy, with the largest proportion of elderly citizens in Europe. Few epidemiological studies have been performed worldwide to estimate the demand for future knee replacement, and a variety of methods have been proposed.

methodsWe investigated the epidemiology of knee arthroplasty performed in Italy in the last 15 years and projected incidence rates up to the year 2050, utilizing, comparing, and adapting the available methodologies.

resultsFrom 2001 to 2016, 812,639 primary TKA were performed in Italy on patients over 40. The total number of surgeries increased by 262% with an average annual growth rate of 6.6%.

conclusionsAdopting the best fitting projection method, an increase of 45% in incidence rate is expected for 2050.

Indexed as

AgedArthroplasty, Replacement, KneeFemaleForecastingHumansItalyMaleMiddle AgedOsteoarthritis, KneeEpidemiologyHospital discharge dataProjectionsTotal knee arthroplasty

Identifiers

PMID30293141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.