Evidence map›Paper›PMID 30293095›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2018

Prevalence and predictors of atrial arrhythmias in patients with sinus node dysfunction and atrial pacing.

Abdallah Bukari, Eisha Wali, Amrish Deshmukh, Zaid Aziz, Michael Broman, Andrew Beaser, Gaurav Upadhyay, Hemal Nayak, Roderick Tung, Cevher Ozcan

Open access · greenAbstract read
In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Differences in functional block during extrastimulation from the right atrial appendage and Bachmann bundle region; a potential mechanism of observed anti-fibrillatory effects of Bachmann bundle pacing.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Abdallah BukariDepartment of Medicine, Section of Cardiology, Center for Arrhythmia Care, Heart and Vascular Center, University of Chicago Medicine Pritzker School of Medicine, 5841 S. Maryland Avenue, MC 6092, Chicago, IL, 60637, USA.
Eisha WaliDepartment of Medicine, Section of Cardiology, Center for Arrhythmia Care, Heart and Vascular Center, University of Chicago Medicine Pritzker School of Medicine, 5841 S. Maryland Avenue, MC 6092, Chicago, IL, 60637, USA.
Amrish DeshmukhDepartment of Medicine, Section of Cardiology, Center for Arrhythmia Care, Heart and Vascular Center, University of Chicago Medicine Pritzker School of Medicine, 5841 S. Maryland Avenue, MC 6092, Chicago, IL, 60637, USA.
Zaid AzizDepartment of Medicine, Section of Cardiology, Center for Arrhythmia Care, Heart and Vascular Center, University of Chicago Medicine Pritzker School of Medicine, 5841 S. Maryland Avenue, MC 6092, Chicago, IL, 60637, USA.
Michael BromanDepartment of Medicine, Section of Cardiology, Center for Arrhythmia Care, Heart and Vascular Center, University of Chicago Medicine Pritzker School of Medicine, 5841 S. Maryland Avenue, MC 6092, Chicago, IL, 60637, USA.
Andrew BeaserDepartment of Medicine, Section of Cardiology, Center for Arrhythmia Care, Heart and Vascular Center, University of Chicago Medicine Pritzker School of Medicine, 5841 S. Maryland Avenue, MC 6092, Chicago, IL, 60637, USA.
Gaurav UpadhyayDepartment of Medicine, Section of Cardiology, Center for Arrhythmia Care, Heart and Vascular Center, University of Chicago Medicine Pritzker School of Medicine, 5841 S. Maryland Avenue, MC 6092, Chicago, IL, 60637, USA.
Hemal NayakDepartment of Medicine, Section of Cardiology, Center for Arrhythmia Care, Heart and Vascular Center, University of Chicago Medicine Pritzker School of Medicine, 5841 S. Maryland Avenue, MC 6092, Chicago, IL, 60637, USA.
Roderick TungDepartment of Medicine, Section of Cardiology, Center for Arrhythmia Care, Heart and Vascular Center, University of Chicago Medicine Pritzker School of Medicine, 5841 S. Maryland Avenue, MC 6092, Chicago, IL, 60637, USA.
Cevher OzcanDepartment of Medicine, Section of Cardiology, Center for Arrhythmia Care, Heart and Vascular Center, University of Chicago Medicine Pritzker School of Medicine, 5841 S. Maryland Avenue, MC 6092, Chicago, IL, 60637, USA. cozcan@uchicago.edu.
University of Chicago · US

Funding

Mitochondrial Mechanisms and Novel Therapeutic Targets in Atrial FibrillationK08HL117082 · NHLBI · UNIVERSITY OF CHICAGO · PI OZCAN, CEVHER · 2014 to 2018
$798k
NHLBI NIH HHS 1K08HL117082-01A4NHLBI NIH HHS K08 HL117082
6 · The paper itself

Abstract

purposeThis study aimed to determine the incidence, prevalence, and predictors of atrial arrhythmias (AAs) in patients with symptomatic sinus node dysfunction (SND) who required permanent pacemaker implantation. Also, we evaluated the impact of atrial pacing (AP) on AAs.

methodsAll consecutive patients who underwent pacemaker implantation from 2005 to 2011 were included. Atrial fibrillation (AF), atrial flutter (AFL), atrial tachycardia (AT), and AV nodal reentrant tachycardia (AVNRT) were detected via pacemaker interrogation and clinical documentation.

resultsThe study group included 322 patients (44% male) with mean age 68.8 ± 15 years and followed for an average of 5.6 ± 2.2 years (median 5.7 years). Overall, 61.8% were found to have any AA at follow-up. Individual prevalence of AAs was high as follows: AF 43.5%, AFL 6.5%, AT 25%, and AVNRT 6.8%. AF was documented in 23% of patients (n = 74) prior to pacemaker; among those, 15% (n = 11) had no recurrence of AF with average AP of 74%. The incidence of new-onset AF after pacemaker was 15.8%. In subgroup analysis, prevalence of AF was increased by 16% with high rate of AP (81-100%) and 17% with lower rate of AP (0-20%). Incidence of new-onset AF was not affected by AP. Diabetes, hypertension, and left atrial enlargement were predictors of AAs. White men and women had higher prevalence of AF.

conclusionsAAs are highly prevalent in SND, particularly in white patients. Paroxysmal AF is suppressed with AP in minority, but there is no impact of AP on new-onset AF. Patients with diabetes, hypertension, and dilated atria must be monitored closely for early detection of AAs.

Indexed as

Sick Sinus SyndromeAgedAged, 80 and overAtrial FibrillationAtrial FlutterCardiac Pacing, ArtificialElectrocardiographyFemaleHumansIncidenceMaleMiddle AgedPacemaker, ArtificialPrevalenceRecurrenceRisk FactorsAtrial arrhythmiasAtrial fibrillationPacemakerSinus node dysfunction

Identifiers

PMID30293095
PMCPMC7134386
OpenAlexW2895487064

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.