Evidence map›Paper›PMID 30292884›Full record

ArticleToxicology letters2018

Role of body composition and physical activity on permethrin urinary biomarker concentrations while wearing treated military uniforms.

Susan P Proctor, Matthew M Scarpaci, Alexis L Maule, Kristin J Heaton, Kathryn Taylor, Caitlin C Haven, Jennifer Rood, Maria Ospina, Antonia M Calafat

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Susan P ProctorUnited States Army Research Institute of Environmental Medicine, Military Performance Division, 10 General Greene Avenue, Natick, MA, USA; VA Boston Healthcare System, Research Service, 180 South Huntington Avenue, Boston, MA, USA; Boston University School of Public Health, Department of Environmental Health, 715 Albany Street, Boston, MA, USA. Electronic address: susan.p.proctor.civ@mail.mil.
Matthew M ScarpaciUnited States Army Research Institute of Environmental Medicine, Military Performance Division, 10 General Greene Avenue, Natick, MA, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, 6720-A Rockledge Drive, Suite 100, Bethesda, MD, USA.
Alexis L MauleUnited States Army Research Institute of Environmental Medicine, Military Performance Division, 10 General Greene Avenue, Natick, MA, USA; Henry M. Jackson Foundation for the Advancement of Military Medicine, 6720-A Rockledge Drive, Suite 100, Bethesda, MD, USA.
Kristin J HeatonUnited States Army Research Institute of Environmental Medicine, Military Performance Division, 10 General Greene Avenue, Natick, MA, USA; Boston University School of Public Health, Department of Environmental Health, 715 Albany Street, Boston, MA, USA.
Kathryn TaylorUnited States Army Research Institute of Environmental Medicine, Military Performance Division, 10 General Greene Avenue, Natick, MA, USA.
Caitlin C HavenUnited States Army Research Institute of Environmental Medicine, Military Performance Division, 10 General Greene Avenue, Natick, MA, USA.
Jennifer RoodLouisiana State University's Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA, USA.
Maria OspinaCenters for Disease Control and Prevention, National Center for Environmental Health, Division of Laboratory Sciences, 4770 Buford Hwy, Atlanta, GA, USA.
Antonia M CalafatCenters for Disease Control and Prevention, National Center for Environmental Health, Division of Laboratory Sciences, 4770 Buford Hwy, Atlanta, GA, USA.
Henry M. Jackson Foundation · USU.S. Army Research Institute of Environmental Medicine · USBoston University · USCenters for Disease Control and Prevention · USLouisiana State University · USNational Center for Environmental Health · USVA Boston Healthcare System · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Wearing of permethrin treated clothing is becoming more prevalent in military and outdoor occupational and recreational settings, as a personal protection measure against vector borne diseases transmitted through arthropods (e.g., malaria, Lyme disease). The goal of the study was to prospectively examine permethrin exposure among new U.S. Army recruits who had just been issued permethrin-treated uniforms over a 10-week military training period and whether individual body composition (percent body fat, %BF) and physical workload (total energy expenditure, TEE) influenced the exposure. Exposure was assessed by quantification in urine of three permethrin metabolites, 3-phenoxybenzoic acid (3-PBA), and cis- and trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane-1-carboxylic acid. Although there was individual variability, urinary concentrations and estimated dose levels decreased over the 10-week period. Mixed models demonstrated that 10% higher %BF was significantly associated with 4.42% higher 3-PBA concentrations and a 10% higher daily TEE was significantly associated with a 10.57% higher 3-PBA concentrations. Additional factors influencing exposure included sex, number of uniform launderings, and wear- time (hours per previous day).

Indexed as

Body CompositionClothingExerciseMilitary PersonnelBiomarkersCohort StudiesFemaleHumansInsecticidesMaleModels, TheoreticalOccupational ExposurePermethrinProspective StudiesSurveys and QuestionnairesTime FactorsBiomarkersInsecticidesPermethrinBody compositionEnergy expenditureMilitaryPercent body fatPermethrinUniforms

Identifiers

PMID30292884
PMCPMC7976610
OpenAlexW2894667619

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.