Evidence map›Paper›PMID 30292777›Full record

ReviewCurrent opinion in psychology2019

The role of genetics in stress effects on health and addiction.

Tony W Buchanan, William R Lovallo

Abstract readReview
In one paragraph

Review in Current opinion in psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Tony W BuchananDepartment of Psychology, Saint Louis University, 3700 Lindell Blvd., St. Louis, MO 63108, USA. Electronic address: tbuchan7@slu.edu.
William R LovalloDepartment of Psychiatry and Behavioral Sciences, University of Oklahoma Health Sciences Center and VA Medical Center, 755 Research Parkway, Oklahoma City, OK 73104, USA.

Funding

Psychophysiological Precursors of AlcoholismR01AA012207 · NIAAA · UNIV OF ARKANSAS FOR MED SCIS · PI ACHESON, ASHLEY, KOCHUNOV, PETER V. · 2001 to 2025
$9.0M
Exercise: Addressing Stress in Relapse Prevention for Substance Use DisordersR01DA033411 · NIDA · SAINT LOUIS UNIVERSITY · PI WEINSTOCK, JEREMIAH · 2013 to 2018
$1.7M
NIAAA NIH HHS R01 AA012207NIDA NIH HHS R01 DA033411
6 · The paper itself

Abstract

Advances in stress research have yielded new insights into how stress exposure, in combination with genetics, can contribute to poor health outcomes. We review these topics with a special emphasis on early life stress and vulnerability to addiction. The direct effects of stress and our compensatory responses can modify our physiology and behavior during future stress episodes. These consequences can influence health, including an increased propensity for addiction. The relation between stress and health is not uniform across individuals. Some people succumb to stress-related disorders while others are resilient. Specific genetic polymorphisms affect how an individual appraises and responds to stress, potentially mediating the impact of stress on health. These genetic vulnerabilities can influence responses to the external environment, shape motivated behavior, and have an impact on health throughout life.

Indexed as

Behavior, AddictiveGene-Environment InteractionHealth StatusChild AbuseChild, PreschoolHumansStress, PsychologicalSubstance-Related Disorders

Identifiers

PMID30292777
PMCPMC6428629

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.