ArticleNeuroImage2019
Mapping the human brain's cortical-subcortical functional network organization.
Article in NeuroImage, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 362 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
362 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Heterogeneous brain alterations in treatment-resistant depression converge on common control networks.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Pooled it
- Network-Level Convergence of Adiposity-Related Gray Matter Alterations: A Coordinate-Based Connectome Mapping Meta-Analysis With Imaging Transcriptomics.Human brain mapping · 2026Pooled it
- A bias-accounting meta-analytic approach refines and expands the cerebellar behavioral topography.Neuroscience and biobehavioral reviews · 2025Pooled it
- Mentalizing About Dynamic Social Action Sequences Is Supported by the Cerebellum, Basal Ganglia, and Neocortex: A Meta-Analysis of Activation and Connectivity.Human brain mapping · 2024Pooled it
- Mapping Cerebellar Connectivity to Cognition in Psychosis: Convergent Evidence From Functional Magnetic Resonance Imaging and Transcranial Magnetic Stimulation.Biological psychiatry · 2026Trial
- Methylphenidate reorganizes cortical hierarchy through dopaminergic modulation.Nature communications · 2025Trial
- A common symptom geometry of mood improvement under sertraline and placebo associated with distinct neural patterns.Psychological medicine · 2025Trial
- Acupuncture modulates emotional network resting-state functional connectivity in patients with insomnia disorder: a randomized controlled trial and fMRI study.BMC complementary medicine and therapies · 2024Trial
- Ketamine induces multiple individually distinct whole-brain functional connectivity signatures.eLife · 2024Trial
- Hemispheric imbalance in mild cognitive impairment: a graph-theoretical analysis of multimodal brain networks.Annals of medicine · 2026Article
- Network-dependent remote effects and local tau burden jointly shape neuronal dysfunction in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Heterogeneous neuroimaging findings in obsessive-compulsive disorder converge to a common brain network using coordinate network mapping.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Article
- Division-Specific Organization of a Shared Functional Scaffold in the Early-Life Human Brain.bioRxiv : the preprint server for biology · 2026Article
- Preserved intrinsic neural timescale organization with hierarchical variation in autism spectrum disorder.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Inferring multi-organ genetic connections using imaging and clinical data through Mendelian randomization.Nature biomedical engineering · 2026Article
- A reproducible low-dimensional architecture of human white-matter connectivity.Research square · 2026Article
- Neural response to reward uncertainty in adolescents with mood and anxiety symptoms.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Model-based semantic distance reveals adaptive coordination of distinct cognitive systems in flexible knowledge retrieval.Nature communications · 2026Article
- Computational Counterfactuals Reveal Non-Additive Audiovisual Semantics in Natural Movie Responses.bioRxiv : the preprint server for biology · 2026Article
- Altered reward-related resting-state network properties in adolescent cannabis use and depression.Progress in neuro-psychopharmacology & biological psychiatry · 2026Article
302 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Understanding complex systems such as the human brain requires characterization of the system's architecture across multiple levels of organization - from neurons, to local circuits, to brain regions, and ultimately large-scale brain networks. Here we focus on characterizing the human brain's large-scale network organization, as it provides an overall framework for the organization of all other levels. We developed a highly principled approach to identify cortical network communities at the level of functional systems, calibrating our community detection algorithm using extremely well-established sensory and motor systems as guides. Building on previous network partitions, we replicated and expanded upon well-known and recently-identified networks, including several higher-order cognitive networks such as a left-lateralized language network. We expanded these cortical networks to subcortex, revealing 358 highly-organized subcortical parcels that take part in forming whole-brain functional networks. Notably, the identified subcortical parcels are similar in number to a recent estimate of the number of cortical parcels (360). This whole-brain network atlas - released as an open resource for the neuroscience community - places all brain structures across both cortex and subcortex into a single large-scale functional framework, with the potential to facilitate a variety of studies investigating large-scale functional networks in health and disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.