Observational studyArchives of physical medicine and rehabilitation2019
Intra- and Interrater Reliability and Concurrent Validity of a New Tool for Assessment of Breast Cancer-Related Lymphedema of the Upper Extremity.
Observational study in Archives of physical medicine and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04766489 (Evaluation of the Treatment Response in Breast Cancer Related Lymphedema After Mastectomy Surgery), which is not on this map. Cited by 9 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Treatment Response in Breast Cancer Related Lymphedema After Mastectomy Surgery
Who cites it
9 citing papers in PubMed.
- Breast cancer-related lymphoedema: approach and management.Singapore medical journal · 2026Article
- Evaluation of response to treatment in breast cancer-related lymphedema.Turkish journal of physical medicine and rehabilitation · 2025Article
- Ultrasound Examination of Skin, Fasciae and Subcutaneous Tissue: Optimizing Rehabilitation for Secondary Upper Limb Lymphedema.Diagnostics (Basel, Switzerland) · 2024Article
- Accuracy of Infrared Thermography in Diagnosing Breast Cancer-Related Lymphedema.Journal of clinical medicine · 2024Article
- Utilization of Noncontrast Magnetic Resonance Lymphangiography for Selection of Effective Surgical Method in Breast Cancer-Related Lymphedema.Medicina (Kaunas, Lithuania) · 2023Article
- Diagnostic Criteria for Breast Cancer-Related Lymphedema of the Upper Extremity: The Need for Universal Agreement.Annals of surgical oncology · 2022Review
- Integrating Symptoms Into the Diagnostic Criteria for Breast Cancer-Related Lymphedema: Applying Results From a Prospective Surveillance Program.Physical therapy · 2020Article
- Features, Predictors, and Treatment of Breast Cancer-related Lymphedema.Current breast cancer reports · 2020Article
- Breast Cancer-Related Lymphedema: Risk Factors, Screening, Management, and the Impact of Locoregional Treatment.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2020Review
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
objectiveThe goal of this study was to develop and assess intra- and interrater reliability and validity of a clinical evaluation tool for breast cancer-related lymphedema, for use in the context of outcome evaluation in clinical trials.
designBlinded repeated measures observational study.
settingOutpatient research laboratory.
participantsBreast cancer survivors with and without lymphedema (N=71).
interventionsNot applicable.
main outcome measureThe assessment of intraclass correlation coefficients (ICCs) for the Breast Cancer-Related Lymphedema of the Upper Extremity (CLUE) standardized clinical evaluation tool.
resultsIntrarater reliability for the CLUE tool was ICC: 0.88 (95% confidence interval [95% CI], 0.71-0.96). Interrater reliability for the CLUE tool was ICC: 0.90 (95% CI, 0.79-0.95). Concurrent validity of the CLUE score (Pearson r) was 0.79 with perometric interlimb difference and 0.53 with the Norman lymphedema overall score.
conclusionsThe CLUE tool shows excellent inter- and intrarater reliability. The overall CLUE score for the upper extremity also shows moderately strong concurrent validity with objective and subjective measures. This newly developed clinical, physical assessment of upper extremity lymphedema provides standardization and a single score that accounts for multiple constructs. Next steps include evaluation of sensitivity to change, which would establish usefulness to evaluate intervention efficacy.
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