ArticleTransfusion2018
Blood transfusions in preterm infants: changes on perfusion index and intermittent hypoxemia.
Article in Transfusion, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Effect of early prophylactic low-dose recombinant human erythropoietin on retinopathy of prematurity in very preterm infants.Journal of translational medicine · 2020Trial
- Short-Term Physiological Effects of Red Blood Cell Transfusion in Very Low Birth Weight Infants: A Retrospective Cohort Study.Children (Basel, Switzerland) · 2026Article
- Minute-by-minute systemic hemodynamic responses to packed red blood cell transfusion in extremely low gestational age neonates: a prospective cohort study.Pediatric research · 2026Article
- Predicting Extubation Readiness in Preterm Infants Utilizing Machine Learning: A Diagnostic Utility Study.The Journal of pediatrics · 2024Observational
- The impact of intermittent hypoxemia on type 1 retinopathy of prematurity in preterm infants.Pediatric research · 2024Article
- Predicting patient decompensation from continuous physiologic monitoring in the emergency department.NPJ digital medicine · 2023Article
- Impact of level of neonatal care on phlebotomy and blood transfusion in extremely low birthweight infants: a prospective, multicenter, observational study.Frontiers in pediatrics · 2023Article
- Evaluation of tissue perfusion status in moderate to late preterm.Physiological research · 2022Article
- The relationship between intermittent hypoxemia events and neural outcomes in neonates.Experimental neurology · 2021Review
- Response to first dose of inhaled albuterol in mechanically ventilated preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Extubation Readiness in Preterm Infants: Evaluating the Role of Monitoring Intermittent Hypoxemia.Children (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
backgroundRed blood cell (RBC) transfusion decreases intermittent hypoxemia (IH) events beyond the first week of life. This benefit may be related to improved perfusion to the respiratory control network. Perfusion index (PI) is a perfusion measure provided by the pulse oximeter. We hypothesized that the benefit in IH after RBC transfusion is associated with an increase in PI. In addition, we assessed the value of PI and clinical measures in predicting the effect of RBC transfusion on IH. STUDY DESIGN AND
methodsWe prospectively enrolled infants less than 30 weeks' gestation age. PI and oxygen saturation (SpO
resultsA total of 118 transfusions were analyzed. IH measures significantly decreased after transfusion in Epochs 2 and 3. PI significantly increased after transfusion, but it did not correlate with the decrease in IH measures. Mechanical ventilation, fraction of inspired oxygen (FiO
conclusionsRBC transfusion improved IH after the first week of life. The benefit in IH did not correlate with PI increase after transfusion. Pretransfusion respiratory support and IH measures predicted the effect of transfusion on oxygenation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.