Evidence map›Paper›PMID 30291617›Full record

ArticleEnvironmental science and pollution research international2018

Transcriptome analysis reveals the molecular response to cadmium toxicity in P. pseudoannulata.

Juan Wang, Baoyang Wei, Yuande Peng, Ting Huang, Huilin Yang, Xianjin Peng, Chunliang Xie, Xiang Xu, Zhiying Sun, Zhi Wang and 2 more

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Article in Environmental science and pollution research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Juan WangCollege of Life Sciences, Hunan Normal University, Changsha, 410081, Hunan, China.
Baoyang WeiCollege of Bioscience and Biotechnology, Hunan Agriculture University, Changsha, 410128, Hunan, China.
Yuande PengInstitute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha, 410205, Hunan, China.
Ting HuangCollege of Bioscience and Biotechnology, Hunan Agriculture University, Changsha, 410128, Hunan, China.
Huilin YangCollege of Bioscience and Biotechnology, Hunan Agriculture University, Changsha, 410128, Hunan, China.
Xianjin PengCollege of Life Sciences, Hunan Normal University, Changsha, 410081, Hunan, China.
Chunliang XieInstitute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha, 410205, Hunan, China.
Xiang XuCollege of Life Sciences, Hunan Normal University, Changsha, 410081, Hunan, China.
Zhiying SunCollege of Bioscience and Biotechnology, Hunan Agriculture University, Changsha, 410128, Hunan, China.
Zhi WangCollege of Life Sciences, Hunan Normal University, Changsha, 410081, Hunan, China. wangzhisipder@hotmail.com.
Zhiyue LvDepartment of Parasitology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China. lvzhiyue@mail.sysu.edu.cn.
Qisheng SongDivision of Plant Sciences, University of Missouri, Columbia, MO, 65211, USA.

Funding

Agricultural Science and Technology Innovation Program of China CAAS-ASTIP-IBFCkey projects of Hunan Provincial Science and Technology Department 2014FJ2003Natural Science Foundation of P. R. China 31272339Natural Science Foundation of P. R. China 31472017Planned Science and Technology Project of Hunan Province, China 2015RS4036postgraduate research projects of Hunan Province, China CX2017B361research project of Hunan Provincial Education Department 15C0666
6 · The paper itself

Abstract

Cadmium (Cd) can be transferred and accumulated in spiders, posing a survival risk to them. To analyze potential biological damage caused by Cd accumulation and relevant detoxification strategies employed by spiders in response to Cd exposure, we conducted transcriptome analysis of the 5th instar spider P. pseudoannulata, a common spider species playing a vital role in natural pest control in agricultural fields of southern China. We obtained 92,778 unigenes with an average length of 1104 bp and identified 302, 655, and 424 differentially expressed genes (DEGs) in the spiders fed with Cd-containing fruit flies for 2, 5, and 8 days, respectively. Results showed that the body mass of Cd-containing P. pseudoannulata were reduced when compared with controls, presumably due to delayed maturation of tissues and organs. Meanwhile, functional analysis of DEGs indicated that Cd may have a negative effect on neural signal transduction and molt cycle of the spider. For defense strategies, detoxification enzymes like glutathione S-transferase (GST), catalase (CAT), superoxide dismutase (SOD), and P450, and typical proteins like heat shock protein and metallothionein were all differentially expressed in response to Cd stress. Besides, innate immune responses like toll-like receptor signaling pathways were also upregulated. Multiple critical Cd-responsive genes involved in biological damage, detoxification, and immune response were identified, providing referable foundation for further research on Cd toxicity to P. pseudoannulata.

Indexed as

AnimalsCadmiumCatalaseChinaEcotoxicologyEnvironmental ExposureGene Expression ProfilingGene Expression RegulationGlutathione TransferaseInactivation, MetabolicMetallothioneinSpidersSuperoxide DismutaseCadmiumCatalaseGlutathione TransferaseMetallothioneinSuperoxide DismutaseCadmiumDetoxificationDevelopmentImmunityP. pseudoannulata

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.