Evidence map›Paper›PMID 30291516›Full record

ReviewCurrent hypertension reports2018

Obesity and Pulmonary Hypertension.

Karnika Ayinapudi, Twinkle Singh, Ayush Motwani, Thierry H Le Jemtel, Suzanne Oparil

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current hypertension reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Cardiometabolic Risk Factors in Women Exposed to High Altitude.International journal of molecular sciences · 2026
    Review
  4. Review
  5. Article
  6. Right ventricular function in pulmonary hypertension and obesity: a cross-sectional cohort study with survival follow-up.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  7. Pulmonary hypertension associated with nonparenchymal restrictive lung diseases.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Gigantomastia as a Cause of Pulmonary Hypertension.Archives of plastic surgery · 2022
    Article
  19. Risk factors associated with pulmonary hypertension in obesity hypoventilation syndrome.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Karnika AyinapudiTulane University Heart and Vascular Institute, 1430 Tulane Ave, SL-48, New Orleans, LA, 70112, USA.
Twinkle SinghTulane University Heart and Vascular Institute, 1430 Tulane Ave, SL-48, New Orleans, LA, 70112, USA.
Ayush MotwaniTulane University Heart and Vascular Institute, 1430 Tulane Ave, SL-48, New Orleans, LA, 70112, USA.
Thierry H Le JemtelTulane University Heart and Vascular Institute, 1430 Tulane Ave, SL-48, New Orleans, LA, 70112, USA. lejemtel@tulane.edu.
Suzanne OparilVascular Biology and Hypertension Program, Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Tulane University · USUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewWhether the present obesity epidemic will increase the prevalence of pulmonary hypertension over the next decades is unclear. We review the obesity-related mechanisms that may further the development and progression of pulmonary hypertension. RECENT

findingsSystemic and local inflammation, insulin resistance and oxidative stress contribute to the pathobiology of obesity and pulmonary arterial hypertension. Preliminary data suggest that expansion of adipose tissue surrounding the pulmonary artery may hasten the progression of pulmonary arterial hypertension in obese persons. Further, obesity-associated cardiac and pulmonary conditions may increase the prevalence of groups 2 and 3 pulmonary hypertension. The obesity epidemic is likely to increase the prevalence of pulmonary arterial hypertension by enabling vascular remodeling. Obesity-associated cardiac and pulmonary conditions will increase pulmonary hypertension prevalence.

Indexed as

Hypertension, PulmonaryDisease ProgressionHumansObesityVascular RemodelingObesityPerivascular adipose tissuePulmonary hypertension

Identifiers

PMID30291516
OpenAlexW2895429631

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.