Evidence map›Paper›PMID 30291458›Full record

ArticleMikrochimica acta2018

Photoelectrochemical determination of the activity of M.SssI methyltransferase, and a method for inhibitor screening.

Xiao Liu, Chenghua Wei, Jing Luo, Yiping Wu, Xiaoyu Guo, Ye Ying, Ying Wen, Haifeng Yang

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xiao LiuThe Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, 100 Guilin Road, Shanghai, 200234, China.
Chenghua WeiThe Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, 100 Guilin Road, Shanghai, 200234, China.
Jing LuoThe Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, 100 Guilin Road, Shanghai, 200234, China.
Yiping WuThe Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, 100 Guilin Road, Shanghai, 200234, China. yipingwu@shnu.edu.cn.
Xiaoyu GuoThe Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, 100 Guilin Road, Shanghai, 200234, China.
Ye YingThe Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, 100 Guilin Road, Shanghai, 200234, China.
Ying WenThe Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, 100 Guilin Road, Shanghai, 200234, China.
Haifeng YangThe Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, 100 Guilin Road, Shanghai, 200234, China. hfyang@shnu.edu.cn.
Shanghai Normal University · CN

Funding

the National Natural Science Foundation of China 21475088the National Natural Science Foundation of China 21507087
6 · The paper itself

Abstract

A photoelectrochemical (PEC) method is described for the determination of the activity of M.SssI methyltransferase (MTase). The assay relies on enzyme-linkage reactions and a DNA intercalator Ru(bpy)

Indexed as

Photochemical ProcessesDNA-Cytosine MethylasesDrug Evaluation, PreclinicalElectrochemistryElectrodesEnzyme AssaysEnzyme InhibitorsHumansLimit of DetectionPolyethyleneimineTin CompoundsDNA-Cytosine MethylasesDNA modification methylase SssIEnzyme Inhibitorsindium tin oxidePolyethyleneimineTin Compounds5-Aza-2′-deoxycytidineDNA methylationDNA restriction endonucleaseEnzyme-linkage reactionsGlutaraldehydePhotoelectrochemical assayPolyethylenimineRu(bpy)2(dppz)2 +S-Adenosyl-L-methionineSnO2 nanoparticle

Identifiers

PMID30291458
OpenAlexW2895600492

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.