Evidence map›Paper›PMID 30291291›Full record

ArticleScientific reports2018

First assessment of the comparative toxicity of ivermectin and moxidectin in adult dung beetles: Sub-lethal symptoms and pre-lethal consequences.

José R Verdú, Vieyle Cortez, Juan Martinez-Pinna, Antonio J Ortiz, Jean-Pierre Lumaret, Jorge M Lobo, Francisco Sánchez-Piñero, Catherine Numa

Erratum issuedOpen access · goldAbstract readComparative Study
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Diseases of Iberian ibex (European journal of wildlife research · 2023
    Review
  5. Article
  6. Experimental removal of nematode parasites increases growth, sprint speed, and mating success in brown anole lizards.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2022
    Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

José R VerdúI.U.I. CIBIO, Universidad de Alicante, Alicante, E-03080, Spain. jr.verdu@ua.es.ORCID http://orcid.org/0000-0002-0805-8341
Vieyle CortezI.U.I. CIBIO, Universidad de Alicante, Alicante, E-03080, Spain.
Juan Martinez-PinnaDepartamento de Fisiología, Genética y Microbiología. Universidad de Alicante, Alicante, E-03080, Spain.
Antonio J OrtizDepartamento de Química Inorgánica y Química Orgánica, Universidad de Jaén, Campus Las Lagunillas, Jaén, E-23071, Spain.
Jean-Pierre LumaretUniversité Paul Valéry Montpellier 3, Univ. Montpellier, EPHE, CNRS, IRD, CEFE UMR 5175, F34000, Université Paul-Valéry Laboratoire Zoogéographie, route de Mende, 34199, Montpellier, cedex 5, France.
Jorge M LoboMuseo Nacional de Ciencias Naturales-CSIC, Departamento de Biogeografía y Cambio Global, José Abascal 2, Madrid, E-28006, Spain.
Francisco Sánchez-PiñeroDepartamento de Zoología, Universidad de Granada, Granada, E-18071, Spain.
Catherine NumaIUCN-Centre for Mediterranean Cooperation, Marie Curie 22, Campanillas, Málaga, E-29590, Spain.
University of Alicante · ESCentre National de la Recherche Scientifique · FRMuseo Nacional de Ciencias Naturales · ESUniversidad de Granada · ESUniversidad de Jaén · ES

Funding

Ministerio de Economía y Competitividad (Ministry of Economy and Competitiveness) CGL2015-68207-R
6 · The paper itself

Abstract

Among macrocyclic lactones (ML), ivermectin (IVM) and moxidectin (MOX) potentially affect all Ecdysozoan species, with dung beetles being particularly sensitive. The comparative effects of IVM and MOX on adult dung beetles were assessed for the first time to determine both the physiological sub-lethal symptoms and pre-lethal consequences. Inhibition of antennal response and ataxia were tested as two intuitive and ecologically relevant parameters by obtaining the lowest observed effect concentration (LOEC) values and interpolating other relevant toxicity thresholds derived from concentration-response curves (IC

Indexed as

AnimalsArthropod AntennaeColeopteraFemaleInhibitory Concentration 50InsecticidesIvermectinLarvaMacrolidesMaleInsecticidesIvermectinMacrolidesmoxidectin

Identifiers

PMID30291291
PMCPMC6173729
OpenAlexW2894588908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.