ArticleScientific reports2018
Evidence of a Causal Role for mid-Ventrolateral Prefrontal Cortex Based Functional Networks in Retrieving High-Fidelity Memory.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Causal involvement of the left angular gyrus in higher functions as revealed by transcranial magnetic stimulation: a systematic review.Brain structure & function · 2023Pooled it
- Brain connectivity changes associated with episodic recollection decline in aging: A review of fMRI studies.Frontiers in aging neuroscience · 2022Pooled it
- Virtual reality video game improves high-fidelity memory in older adults.Scientific reports · 2021Trial
- The prefrontal cortex across scales: laminar architecture, white-matter constraints, and distributed control in cognition.Brain structure & function · 2026Review
- Hippocampal formation-cortical high-fidelity memory networks in healthy older adults during the mnemonic discrimination task.Frontiers in aging neuroscience · 2026Article
- Hippocampal-prefrontal connectivity relates to inter-individual differences and training gains in distinguishing similar memories.Communications biology · 2025Article
- Demands on perceptual and mnemonic fidelity are a key determinant of age-related cognitive decline throughout the lifespan.Journal of experimental psychology. General · 2024Article
- Parsing memory and nonmemory contributions to age-related declines in mnemonic discrimination performance: a hierarchical Bayesian diffusion decision modeling approach.Learning & memory (Cold Spring Harbor, N.Y.) · 2023Article
- Gamma neuromodulation improves episodic memory and its associated network in amnestic mild cognitive impairment: a pilot study.Neurobiology of aging · 2023Article
- RNA sequencing-based identification of the regulatory mechanism of microRNAs, transcription factors, and corresponding target genes involved in vascular dementia.Frontiers in neuroscience · 2022Article
- Article
- Dissociation of the Perirhinal Cortex and Hippocampus During Discriminative Learning of Similar Objects.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Frontal Contribution to Hippocampal Hyperactivity During Memory Encoding in Aging.Frontiers in molecular neuroscience · 2019Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Functional neuroimaging studies have implicated regions of both ventrolateral prefrontal cortex (VLPFC) and angular gyrus in processes associated with retrieving goal-relevant information, which increases the fidelity and richness of long-term memory (LTM). To further investigate the roles of these cortical regions as nodes in functional networks with memory regions of the medial temporal lobe (MTL), we used fMRI-guided, 1 Hz repetitive transcranial magnetic stimulation (rTMS) to perturb normal neuronal function. The aim was to test the causal roles of left mid-VLPFC and left angular gyrus (AG) in MTL-VLPFC-parietal networks that have been associated with high-fidelity memory retrieval. rTMS treatments were administered immediately before blocks in an old/new recognition test, which was based on a mnemonic similarity task requiring discrimination of previously studied pictures of common objects. Capability for mnemonic discrimination was evaluated after each of three conditions: placebo control (rTMS at somatosensory cortex), mid-VLPFC target (rTMS at left pars triangularis) and parietal target (rTMS at left AG). The results showed the effect of rTMS perturbation of mid-VLPFC diminished subsequent discrimination-based memory performance, relative to placebo control, and no significant effect of perturbation of AG. These findings show a causal role for functional networks with left mid-VLPFC in high-fidelity retrieval.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.