ArticleNature communications2018
A rapid rate of sex-chromosome turnover and non-random transitions in true frogs.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 129 papers.
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Who cites it
129 citing papers in PubMed, 243 citations in OpenAlex.
- Evolution of a ZW sex determination system in sticklebacks.Science advances · 2026Article
- Rapid turnover of sex-determining architecture in invasive mussels.bioRxiv : the preprint server for biology · 2026Article
- Multiple Origins of a Sex Ratio Supergene in Formica Ants.Molecular biology and evolution · 2026Article
- Causes and consequences of sex-chromosome turnovers in Diptera.Evolution letters · 2026Article
- Chromosome-specific drift under stabilizing selection generates polygenic barriers to sex chromosome turnover.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Genome-Wide Characterization of Sex-Linked Regions in the Sangzhi Horned Toad (Boulenophrys sangzhiensis) Reveals Complex Sex Determination Mechanisms.Molecular ecology resources · 2026Article
- Whole-genome sequencing reveals a possible molecular basis of sex determination in the dioecious wild yam Dioscorea tokoro.PLoS genetics · 2026Article
- Sex chromosome evolution mediated by a large inversion and a possible switch of the sex determination gene.Genome biology · 2026Article
- Navigating the Semantic Labyrinth of "Sex" in the Study of Reproductive Trait Evolution.Integrative and comparative biology · 2026Article
- Identification of Male-Specific Markers by Genotyping-by-Sequencing in the Giant Spiny Frog,Genes · 2025Article
- ZW and XY Sex Chromosomes Drive Rapid and Distinctive Evolution of Sex-Biased Gene Expression.Molecular ecology · 2025Article
- Genome Architecture and Speciation in Plants and Animals.Molecular ecology · 2025Review
- Gene Duplication, Translocation, and Molecular Evolution ofBiomolecules · 2025Article
- Chromosome-level genome assembly of the Tyrrhenian tree frog (Hyla sarda).Scientific data · 2025Article
- Identification of Y-chromosome Turnover in Newts Fails to Support a Sex Chromosome Origin for the Triturus Balanced Lethal System.Genome biology and evolution · 2025Article
- The Tree of Sex consortium: a global initiative for studying the evolution of reproduction in eukaryotes.Journal of evolutionary biology · 2025Article
- An Extension of Muller's Sheltering Hypothesis for the Evolution of Sex Chromosome Gene Content.Molecular biology and evolution · 2025Article
- Sharks and rays have the oldest vertebrate sex chromosome with unique sex determination mechanisms.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Sex-biased expression of sex-linked transcripts in spiny frogs with homomorphic sex chromosomes.BMC genomics · 2025Article
- The Heterogametic Transition in European Bufo Toads Switches the Sex Linkage of Key Vertebrate Sex Determination Genes and Associates with a Large Sex Chromosome Effect.Molecular biology and evolution · 2025Article
69 more citing papers are in PubMed but not listed here.
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Authors and funding
23 authors at 15 institutions in 10 countries.
Funding
Abstract
The canonical model of sex-chromosome evolution predicts that, as recombination is suppressed along sex chromosomes, gametologs will progressively differentiate, eventually becoming heteromorphic. However, there are numerous examples of homomorphic sex chromosomes across the tree of life. This homomorphy has been suggested to result from frequent sex-chromosome turnovers, yet we know little about which forces drive them. Here, we describe an extremely fast rate of turnover among 28 species of Ranidae. Transitions are not random, but converge on several chromosomes, potentially due to genes they harbour. Transitions also preserve the ancestral pattern of male heterogamety, in line with the 'hot-potato' model of sex-chromosome transitions, suggesting a key role for mutation-load accumulation in non-recombining genomic regions. The importance of mutation-load selection in frogs might result from the extreme heterochiasmy they exhibit, making frog sex chromosomes differentiate immediately from emergence and across their entire length.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.