ArticleBreast cancer research : BCR2018
Long-term exposure to road traffic noise and incidence of breast cancer: a cohort study.
Article in Breast cancer research : BCR, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Environmental Noise Exposure and Risk of Cancer: A Systematic Review and Meta-Analysis.Current environmental health reports · 2025Pooled it
- Night-shift work, breast cancer incidence, and all-cause mortality: an updated meta-analysis of prospective cohort studies.Sleep & breathing = Schlaf & Atmung · 2022Pooled it
- Evidence for Environmental Noise Effects on Health for the United Kingdom Policy Context: A Systematic Review of the Effects of Environmental Noise on Mental Health, Wellbeing, Quality of Life, Cancer, Dementia, Birth, Reproductive Outcomes, and Cognition.International journal of environmental research and public health · 2020Pooled it
- Association between noise pollution exposure and incident breast cancer in the Sister Study.Environmental research · 2026Article
- Outdoor Exposure to Artificial Light at Night and Breast Cancer Risk: A Case-Control Study Nested in the E3N-Generations Cohort.Environmental health perspectives · 2025Article
- Road traffic noise and breast cancer: DNA methylation in four core circadian genes.Clinical epigenetics · 2024Article
- Breast Cancer Exposomics.Life (Basel, Switzerland) · 2024Review
- Health position paper and redox perspectives - Disease burden by transportation noise.Redox biology · 2024Review
- Effects of Aircraft Noise on Sleep: Federal Aviation Administration National Sleep Study Protocol.International journal of environmental research and public health · 2023Article
- A Narrative Review of the Carcinogenic Effect of Night Shift and the Potential Protective Role of Melatonin.Cureus · 2023Review
- Omics-Based Investigations of Breast Cancer.Molecules (Basel, Switzerland) · 2023Review
- Treatments and regulatory mechanisms of acoustic stimuli on mood disorders and neurological diseases.Frontiers in neuroscience · 2023Review
- Light at night and the risk of breast cancer: Findings from the Sister study.Environment international · 2022Article
- Environmental Conditions of Dance Rooms and Its Impact on Dance Conservatories Teachers' Health (An Andalusian Study).International journal of environmental research and public health · 2021Article
- Monitoring Sound and Its Perception during the Lockdown and De-Escalation of COVID-19 Pandemic: A Spanish Study.International journal of environmental research and public health · 2021Article
- Genome-Wide DNA Methylation in Peripheral Blood and Long-Term Exposure to Source-Specific Transportation Noise and Air Pollution: The SAPALDIA Study.Environmental health perspectives · 2020Article
- The Immune System Can Hear Noise.Frontiers in immunology · 2020Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExposure to road traffic noise was associated with increased risk of estrogen receptor (ER)-negative (ER-) breast cancer in a previous cohort study, but not with overall or ER-positive (ER+) breast cancer, or breast cancer prognosis. We examined the association between long-term exposure to road traffic noise and incidence of breast cancer, overall and by ER and progesterone receptor (PR) status.
methodsWe used the data from a nationwide Danish Nurse Cohort on 22,466 female nurses (age > 44 years) who at recruitment in 1993 or 1999 reported information on breast cancer risk factors. We obtained data on the incidence of breast cancer from the Danish Cancer Registry, and on breast cancer subtypes by ER and PR status from the Danish Breast Cancer Cooperative Group, up to 31 December 2012. Road traffic noise levels at the nurses' residences were estimated by the Nord2000 method between 1970 and 2013 as annual means of a weighted 24 h average (L
resultsOf the 22,466 women, 1193 developed breast cancer in total during 353,775 person-years of follow up, of whom 611 had complete information on ER and PR status. For each 10 dB increase in 24-year mean noise levels at their residence, we found a statistically significant 10% (hazard ratio and 95% confidence interval 1.10; 1.00-1.20) increase in total breast cancer incidence and a 17% (1.17; 1.02-1.33) increase in analyses based on 611 breast cancer cases with complete ER and PR information. We found positive, statistically significant association between noise levels and ER+ (1.23; 1.06-1.43, N = 494) but not ER- (0.93; 0.70-1.25, N = 117) breast cancers, and a stronger association between noise levels and PR+ (1.21; 1.02-1.42, N = 393) than between noise levels and PR- (1.10; 0.89-1.37, N = 218) breast cancers. Association between noise and ER+ breast cancer was statistically significantly stronger in nurses working night shifts (3.36; 1.48-7.63) than in those not working at night (1.21; 1.02-1.43) (p value for interaction = 0.05).
conclusionLong-term exposure to road traffic noise may increase risk of ER+ breast cancer.
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