Evidence map›Paper›PMID 30290796›Full record

ArticleBMC nephrology2018

Factors associated with anaemia in kidney transplant recipients in the first year after transplantation: a cross-sectional study.

Andy K H Lim, Arushi Kansal, John Kanellis

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Andy K H LimDepartment of Nephrology, Monash Health, Clayton, Victoria, 3168, Australia. andy.lim@monash.edu.ORCID 0000-0001-7816-4724
Arushi KansalDepartment of Nephrology, Monash Health, Clayton, Victoria, 3168, Australia.
John KanellisDepartment of Nephrology, Monash Health, Clayton, Victoria, 3168, Australia.
Monash Health · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnaemia after kidney transplantation may reduce quality of life, graft or patient survival. We aimed to determine the prevalence and risk factors for anaemia in the initial 12 months after transplantation.

methodsWe conducted a cross-sectional study at 6 and 12 months after transplantation. Anaemia was defined by World Health Organization criteria taking into consideration erythropoietin use. Logistic regression was used to determine the association between demographic, clinical and pharmacological risk factors for the main outcome of moderate-severe anaemia.

resultsA total of 336 transplant recipients were included and the prevalence of moderate-severe anaemia was 27.4% at 6 months and 15.2% at 12 months. Lower kidney function, female gender, transferrin saturation below 10% and proteinuria were associated with moderate-severe anaemia at both time points. Recent intravenous immunoglobulin treatment was associated with anaemia at 6 months. Recent infection and acute rejection were also associated with anaemia 12 months. Around 20% of patients had at least one blood transfusion but they were uncommon beyond 3 months.

conclusionsAnaemia remains highly prevalent requiring treatment with erythropoietin and transfusions. Most identifiable risk factors relate to clinical problems rather than pharmacological management, while markers of iron-deficiency remain difficult to interpret in this setting.

Indexed as

AdultAnemiaBlood TransfusionCross-Sectional StudiesErythropoietinFemaleGraft SurvivalHematinicsHumansImmunoglobulins, IntravenousImmunosuppressive AgentsKidney TransplantationMaleMiddle AgedPostoperative ComplicationsQuality of LifeErythropoietinHematinicsImmunoglobulins, IntravenousImmunosuppressive AgentsAnaemiaBlood transfusionHaematinicsHaemoglobinIron-deficiencyKidney transplantation

Identifiers

PMID30290796
PMCPMC6173839
OpenAlexW2894833718

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.