ArticleBMC microbiology2018
The palatine tonsil bacteriome, but not the mycobiome, is altered in HIV infection.
Article in BMC microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 24 citations in OpenAlex.
- Analysis of pharyngeal microbiome characteristics in HIV-infected individuals: correlation between the degree of immunosuppression and microbial dysbiosis.BMC infectious diseases · 2026Article
- Article
- Narrative review of application of metagenomic approaches to study the link between oropharyngeal microbiome and infectious diseases.Frontiers in microbiology · 2023Review
- Functional biomes beyond the bacteriome in the oral ecosystem.The Japanese dental science review · 2022Review
- Analysis of Microorganism Colonization, Biofilm Production, and Antibacterial Susceptibility in Recurrent Tonsillitis and Peritonsillar Abscess Patients.International journal of molecular sciences · 2022Article
- Mucosal immune cell populations and the bacteriome of adenoids and tonsils from people living with HIV on suppressive antiretroviral therapy.Frontiers in microbiology · 2022Article
- Effect of HIV/HAART and Other Clinical Variables on the Oral Mycobiome Using Multivariate Analyses.mBio · 2021Article
- The Role of Bacterial and Fungal Human Respiratory Microbiota in COVID-19 Patients.BioMed research international · 2021Review
- Altered Salivary Microbiome in the Early Stage of HIV Infections among Young Chinese Men Who Have Sex with Men (MSM).Pathogens (Basel, Switzerland) · 2020Article
- Oral mycobiome identification in atopic dermatitis, leukemia, and HIV patients - a systematic review.Journal of oral microbiology · 2020Review
- The Human Oral Microbiome in Health and Disease: From Sequences to Ecosystems.Microorganisms · 2020Review
- Review
- JunB plays a crucial role in development of regulatory T cells by promoting IL-2 signaling.Mucosal immunology · 2019Article
- Fungal-Bacterial Interactions in Health and Disease.Pathogens (Basel, Switzerland) · 2019Review
- Interactions among the mycobiome, bacteriome, inflammation, and diet in people living with HIV.Gut microbesArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMicrobial flora in several organs of HIV-infected individuals have been characterized; however, the palatine tonsil bacteriome and mycobiome and their relationship with each other remain unclear. Determining the palatine tonsil microbiome may provide a better understanding of the pathogenesis of oral and systemic complications in HIV-infected individuals. We conducted a cross-sectional study to characterize the palatine tonsil microbiome in HIV-infected individuals.
resultsPalatine tonsillar swabs were collected from 46 HIV-infected and 20 HIV-uninfected individuals. The bacteriome and mycobiome were analyzed by amplicon sequencing using Illumina MiSeq. The palatine tonsil bacteriome of the HIV-infected individuals differed from that of HIV-uninfected individuals in terms of the decreased relative abundances of the commensal genera Neisseria and Haemophilus. At the species level, the relative abundances and presence of Capnocytophaga ochracea, Neisseria cinerea, and Selenomonas noxia were higher in the HIV-infected group than those in the HIV-uninfected group. In contrast, fungal diversity and composition did not differ significantly between the two groups. Microbial intercorrelation analysis revealed that Candida and Neisseria were negatively correlated with each other in the HIV-infected group. HIV immune status did not influence the palatine tonsil microbiome in the HIV-infected individuals.
conclusionsHIV-infected individuals exhibit dysbiotic changes in their palatine tonsil bacteriome, independent of immunological status.
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