Evidence map›Paper›PMID 30290302›Full record

ArticleRedox biology2019

Hydroxycobalamin catalyzes the oxidation of diethyldithiocarbamate and increases its cytotoxicity independently of copper ions.

M E Solovieva, Yu V Shatalin, V V Solovyev, A V Sazonov, V P Kutyshenko, V S Akatov

Open access · goldAbstract read
In one paragraph

Article in Redox biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Vitamin BBiomolecules · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

M E SolovievaInstitute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region 142290 Russia.
Yu V ShatalinInstitute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region 142290 Russia.
V V SolovyevJSC BIOCAD, Saint-Petersburg 198515, Russia.
A V SazonovJSC BIOCAD, Saint-Petersburg 198515, Russia.
V P KutyshenkoInstitute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region 142290 Russia.
V S AkatovInstitute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region 142290 Russia. Electronic address: akatov@iteb.ru.
Institute of Theoretical and Experimental Biophysics · RUBIOCAD (Russia) · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is known that some metals (Cu, Zn, Cd, Au) markedly increase the toxic effect of thiocarbamates. It was shown in the present study that hydroxycobalamin (a form of vitamin B

Indexed as

Oxidation-ReductionCell LineCell SurvivalCopperDitiocarbHumansHydrogen PeroxideHydroxocobalaminIonsOxidative StressSpectrum AnalysisCopperDitiocarbHydrogen PeroxideHydroxocobalaminIonsCytotoxicityDiethyldithiocarbamateDisulfiramHydroxycobalaminOxidative stressVitamin B(12)

Identifiers

PMID30290302
PMCPMC6171330
OpenAlexW2893792155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.