Evidence map›Paper›PMID 30290173›Full record

ArticleCell stem cell2018

3D Human Esophageal Epithelium Steps Out from hPSCs.

Anil K Rustgi

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell stem cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Anil K RustgiUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA. Electronic address: anil2@pennmedicine.upenn.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human pluripotent stem cell (hPSC)-derived organoids can reveal important principles underlying tissue development. In this issue of Cell Stem Cell, Zhang et al. (2018) and Trisno et al. (2018) establish protocols for generating esophageal epithelial cells and 3D stratified epithelium from hPSCs, revealing roles for key signaling pathways and how they are controlled by critical transcription factors.

Indexed as

OrganoidsPluripotent Stem CellsCell DifferentiationEpithelial CellsHumansSignal TransductionSOXB1 Transcription FactorsSOX2 protein, humanSOXB1 Transcription Factors

Identifiers

PMID30290173

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.