Evidence map›Paper›PMID 30290145›Full record

ArticleCell2018

SnapShot: RNA Structure Probing Technologies.

Paul D Carlson, Molly E Evans, Angela M Yu, Eric J Strobel, Julius B Lucks

Abstract read
In one paragraph

Article in Cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Tracking RNA structures as RNAs transit through the cell.Nature structural & molecular biology · 2019
    Article
  8. Combinatorial regulation of alternative splicing.Biochimica et biophysica acta. Gene regulatory mechanisms
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Paul D CarlsonRobert F. Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca NY; Center for Synthetic Biology, Northwestern University, Evanston IL.
Molly E EvansDepartment of Chemical and Biological Engineering, Northwestern University, Evanston IL.
Angela M YuCenter for Synthetic Biology, Northwestern University, Evanston IL; Tri-institutional Training Program in Computational Biology and Medicine, Weill Cornell Medicine, New York, NY.
Eric J StrobelDepartment of Chemical and Biological Engineering, Northwestern University, Evanston IL.
Julius B LucksCenter for Synthetic Biology, Northwestern University, Evanston IL; Department of Chemical and Biological Engineering, Northwestern University, Evanston IL.

Funding

Tri-Institutional Training Program in Computational Biology & MedicineT32GM083937 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHRISTINI, DAVID J. · 2009 to 2018
$3.1M
A New High-Throughput Technology To Reveal The Dynamic Functional States of RNAsDP2GM110838 · NIGMS · NORTHWESTERN UNIVERSITY · PI LUCKS, JULIUS BEAU · 2013 to 2013
$2.1M
Dissecting functional cooperation among subunits in a catalytic ribonucleoproteinR01GM120582 · NIGMS · OHIO STATE UNIVERSITY · PI GOPALAN, VENKAT · 2016 to 2019
$1.9M
NIGMS NIH HHS DP2 GM110838NIGMS NIH HHS R01 GM120582NIGMS NIH HHS T32 GM083937
6 · The paper itself

Abstract

Chemical probing coupled to high-throughput sequencing offers a flexible approach to uncover many aspects of RNA structure relevant to its cellular function. With a wide variety of chemical probes available that each report on different features of RNA molecules, a broad toolkit exists for investigating in vivo and in vitro RNA structure and interactions with other molecules.

Indexed as

AnimalsComputational BiologyHigh-Throughput Nucleotide SequencingHumansNucleic Acid ConformationRNASequence Analysis, RNASoftwareRNA

Identifiers

PMID30290145
PMCPMC6582637

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.