Observational studyJournal of diabetes investigation2019
Contribution of pancreatic α-cell function to insulin sensitivity and glycemic variability in patients with type 1 diabetes.
Observational study in Journal of diabetes investigation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Associations of Plasma Glucagon Levels with Estimated Glomerular Filtration Rate, Albuminuria and Diabetic Kidney Disease in Patients with Type 2 Diabetes Mellitus.Diabetes & metabolism journal · 2021Article
- Blood glucose control: Where are we?Journal of diabetes investigation · 2021Article
- The Role of Glucagon in Glycemic Variability in Type 1 Diabetes: A Narrative Review.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Review
- Beginning of a new era in glucagon research: Breakthrough by the new glucagon assay.Journal of diabetes investigation · 2020Article
- Contribution of pancreatic α-cell function to insulin sensitivity and glycemic variability in patients with type 1 diabetes.Journal of diabetes investigation · 2019Observational
- Glucagon secretions are impaired in patients with fulminant type 1 diabetes.Journal of diabetes investigation · 2019Article
- Metabolic effects of glucagon in humans.Journal of clinical & translational endocrinology · 2019Review
- PARP-14 Promotes Survival of Mammalian α but Not β Pancreatic Cells Following Cytokine Treatment.Frontiers in endocrinology · 2019Article
- Response to "Preserved" glucagon secretion in fulminant type 1 diabetes.Journal of diabetes investigation · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
AIMS/
introductionTo evaluate the contribution of pancreatic α-cell function to the dawn phenomenon, insulin sensitivity, hepatic glucose uptake and glycemic variability in patients with type 1 diabetes. MATERIALS AND
methodsIn 40 patients with type 1 diabetes, arginine stimulation tests were carried out, and the area under the curve (AUC) of glucagon was measured using radioimmunoassays (AUC
resultsThe median dawn index (1.7, interquartile range 1.0-2.8) was not correlated with AUC
conclusionsPancreatic α-cell function contributed to insulin sensitivity in patients with type 1 diabetes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.