Evidence map›Paper›PMID 30289927›Full record

ArticlePloS one2018

Clinical significance of the Kidney Donor Profile Index in deceased donors for prediction of post-transplant clinical outcomes: A multicenter cohort study.

Jong Hoon Lee, Woo Yeong Park, Young Soo Kim, Bum Soon Choi, Cheol Whee Park, Chul Woo Yang, Yong-Soo Kim, Kyubok Jin, Seungyeup Han, Byung Ha Chung

Abstract readMulticenter Study
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jong Hoon LeeTransplant Research Center, Seoul St. Mary's Hospital, Seoul, Korea.
Woo Yeong ParkDepartment of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.
Young Soo KimDivision of Nephrology, Department of Internal Medicine, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Uijongbu, Korea.
Bum Soon ChoiDivision of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Cheol Whee ParkDivision of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Chul Woo YangTransplant Research Center, Seoul St. Mary's Hospital, Seoul, Korea.
Yong-Soo KimTransplant Research Center, Seoul St. Mary's Hospital, Seoul, Korea.
Kyubok JinDepartment of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.
Seungyeup HanDepartment of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.
Byung Ha ChungTransplant Research Center, Seoul St. Mary's Hospital, Seoul, Korea.ORCID 0000-0003-0048-5717

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe investigated whether the Kidney Donor Profile Index (KDPI) system is useful in predicting clinical outcomes in deceased donor kidney transplantation (DDKT).

methodsFour hundred sixty-nine kidney transplant recipients (KTRs) receiving kidneys from 359 deceased donors were included in this study, which involved three transplant centers. KTRs were divided into high and low KDPI KTR groups based on the median KDPI score of 67%. We compared clinical outcomes between the high KDPI and low KDPI groups.

resultsThere were no significant differences in the incidence of delayed graft function and acute rejection between high and low KDPI KTR groups. In comparison with histologic findings in allograft tissues obtained within three months from KT, the proportion of glomerulosclerosis was significantly higher in the high KDPI KTR group than in the low KDPI KTR group. With Kaplan-Meier analysis, the graft survival rate was significantly lower in the high KDPI KTR group than in the low KDPI KTR group (Log rank, P = 0.017), and multivariate analysis also demonstrated that a high KDPI score was a significant risk factor for death censored allograft failure (HR 2.62, 95% CI, 1.29-5.33, P = 0.008).

conclusionThe KDPI scoring system is useful in predicting allograft outcomes in a Korean DDKT cohort.

Indexed as

DeathAdultBody Mass IndexCohort StudiesFemaleGraft RejectionGraft SurvivalHumansKidney TransplantationMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsTissue Donors

Identifiers

PMID30289927
PMCPMC6173429

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.