ArticlePLoS medicine2018
Expected changes in obesity after reformulation to reduce added sugars in beverages: A modeling study.
Article in PLoS medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Calorie (energy) labelling for changing selection and consumption of food or alcohol.The Cochrane database of systematic reviews · 2025Pooled it
- Pooled it
- Relation of Change or Substitution of Low- and No-Calorie Sweetened Beverages With Cardiometabolic Outcomes: A Systematic Review and Meta-analysis of Prospective Cohort Studies.Diabetes care · 2022Pooled it
- The food environment in Latin America: a systematic review with a focus on environments relevant to obesity and related chronic diseases.Public health nutrition · 2019Pooled it
- Dietary Supplementation of L-Carnosine Attenuates High Starch-Induced Disorders of Carbohydrate and Lipid Metabolisms in Zebrafish.International journal of molecular sciences · 2026Article
- Sugar Reformulation in Solid Foods: Limitations and Challenges.Nutrition bulletin · 2025Article
- Associated substitution and complementation patterns of processed discretionary foods and drinks on total energy and added sugar intake.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2023Article
- Health and economic burden of sugar-sweetened beverages consumption in Brazil.Cadernos de saude publica · 2023Article
- [Burden of disease and economic burden attributable to the consumption of sugar-sweetened beverages in El SalvadorCarga de morbidade e econômica atribuível ao consumo de bebidas açucaradas em El Salvador].Revista panamericana de salud publica = Pan American journal of public health · 2023Article
- The burden of disease and economic impact of sugar-sweetened beverages' consumption in Argentina: A modeling study.PloS one · 2023Article
- The nutrition transition to a stage of high obesity and noncommunicable disease prevalence dominated by ultra-processed foods is not inevitable.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022Article
- Article
- Article
- Towards unified and impactful policies to reduce ultra-processed food consumption and promote healthier eating.The lancet. Diabetes & endocrinology · 2021Review
- Fructose and the Liver.International journal of molecular sciences · 2021Review
- Role of different nutrient profiling models in identifying targeted foods for front-of-package food labelling in Brazil.Public health nutrition · 2021Article
- Article
- Sugar-sweetened beverage consumption and risk of hyperuricemia: a longitudinal analysis of the Health Workers Cohort Study participants in Mexico.The American journal of clinical nutrition · 2020Article
- Predicting obesity reduction after implementing warning labels in Mexico: A modeling study.PLoS medicine · 2020Article
- Mortality attributable to sugar sweetened beverages consumption in Mexico: an update.International journal of obesity (2005) · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors.
Funding
Abstract
backgroundSeveral strategies have been proposed to reduce the intake of added sugars in the population. In Mexico, a 10% sugar-sweetened beverages (SSBs) tax was implemented in 2014, and the implementation of other nutritional policies, such as product reformulation to reduce added sugars, is under discussion. WHO recommends that all individuals consume less than 10% of their total energy intake (TEI) from added sugars. We propose gradually reducing added sugars in SSBs to achieve an average 10% consumption of added sugars in the Mexican population over 10 years and to estimate the expected impact of reformulation in adult body weight and obesity. METHODS AND
findingsBaseline consumption for added sugars and SSBs, sex, age, socioeconomic status (SES), height, and weight for Mexican adults were obtained from the 2012 Mexico National Health and Nutrition Survey (ENSANUT). On average, 12.6% of the TEI was contributed by added sugars; we defined a 50% reduction in added sugars in SSBs over 10 years as a reformulation target. Using a dynamic weight change model, sugar reductions were translated into individual expected changes in body weight assuming a 43% caloric compensation and a 2-year lag for the full effect of reformulation to occur. Results were stratified by sex, age, and SES. Twelve years after reformulation, the TEI from added sugars is expected to decrease to 10%, assuming no compensation from added sugars; 44% of the population would still be above WHO recommendations, requiring further sugar reductions to food. Body weight could be reduced by 1.3 kg (95% CI -1.4 to -1.2) in the adult population, and obesity could decrease 3.9 percentage points (pp; -12.5% relative to baseline). Our sensitivity analyses suggest that the impact of the intervention could vary from 0.12 kg after 6 months to 1.52 kg in the long term.
conclusionsReformulation to reduce added sugars in SSBs could produce large reductions in sugar consumption and obesity in the Mexican adult population. This study is limited by the use of a single dietary recall and by data collected in all seasons except summer; still, these limitations should lead to conservative estimates of the reformulation effect. Reformulation success could depend on government enforcement and industry and consumer response, for which further research and evidence are needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.